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植入皮质酮和/或饲喂抗坏血酸的肉鸡肝脏微粒体混合功能氧化酶系统及抗体产生的性别相关差异

Sex-related differences of hepatic microsomal mixed function oxidase system and antibody production in broilers implanted with corticosterone and/or fed ascorbic acid.

作者信息

Takahashi K, Akiba Y, Horiguchi M

机构信息

Department of Animal Science, Faculty of Agriculture, Tohoku University, Sendai-Shi, Japan.

出版信息

Comp Biochem Physiol C Comp Pharmacol Toxicol. 1993 Jun;105(2):159-64. doi: 10.1016/0742-8413(93)90188-q.

DOI:10.1016/0742-8413(93)90188-q
PMID:8103725
Abstract
  1. Most of the components of the mixed function oxidase (MFO) in hepatic microsomes were reduced by corticosterone implants, and the degree of the reduction in females and at an older age was greater than those in males and at a younger age. 2. Ascorbic acid (AA) prevented the reduction in the MFO caused by corticosterone implants. 3. The activities of aniline hydroxylase and aminopyrine N-demethylase were enhanced by corticosterone implants regardless of AA supplementation. 4. The activity of NADPH-cytochrome c reductase in male broiler was greater than that in females under normal conditions. 5. Corticosterone implants and dietary AA had less influence on the antibody production, especially to T-cell dependent antigen.
摘要
  1. 肝微粒体中混合功能氧化酶(MFO)的大多数成分因植入皮质酮而减少,且雌性和老年个体的减少程度大于雄性和年轻个体。2. 抗坏血酸(AA)可防止因植入皮质酮而导致的MFO减少。3. 无论是否补充AA,植入皮质酮均可增强苯胺羟化酶和氨基比林N-脱甲基酶的活性。4. 在正常条件下,雄性肉鸡中NADPH-细胞色素c还原酶的活性高于雌性。5. 植入皮质酮和日粮中的AA对抗体产生的影响较小,尤其是对T细胞依赖性抗原的影响。

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