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饮食如何影响大鼠的衰老过程。

How diet influences the aging process of the rat.

作者信息

Yu B P

机构信息

Department of Physiology, University of Texas Health Science Center, San Antonio 78284-7756.

出版信息

Proc Soc Exp Biol Med. 1994 Feb;205(2):97-105. doi: 10.3181/00379727-205-43684.

DOI:10.3181/00379727-205-43684
PMID:8108472
Abstract

Aging is a time-dependent, deleterious process known to be influenced by multiple factors and processes. Recent gerontological investigations have clearly shown nutrition to be the most powerful extrinsic factor influencing the aging process. That role has been clarified by recent inquiries on such underfeeding paradigms as calorie restriction. The idea of reduced calorie intake as a potent aging modulator contrasts dramatically with the traditional view that "more is better" which springs from the consideration of nutrition only as a source of energy and nutrients required to maintain health. This review presents pertinent data on how nutrition may influence the longevity of organisms and modulate age-related diseases.

摘要

衰老 是一个随时间推移的有害过程,已知受多种因素和进程影响。近期老年学研究清楚表明,营养是影响衰老过程的最强大外部因素。近期关于诸如热量限制等低热量摄入模式的研究已阐明了这一作用。将减少热量摄入视为一种有效的衰老调节因素,这一观点与传统的“越多越好”观点形成了鲜明对比,后者源于仅将营养视为维持健康所需能量和营养物质来源的考量。本综述展示了关于营养如何影响生物体寿命以及调节与年龄相关疾病的相关数据。

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1
How diet influences the aging process of the rat.饮食如何影响大鼠的衰老过程。
Proc Soc Exp Biol Med. 1994 Feb;205(2):97-105. doi: 10.3181/00379727-205-43684.
2
Nutrition and energetics in rodent longevity research.啮齿动物长寿研究中的营养与能量学
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Retardation of the aging processes in rats by food restriction.通过限制饮食延缓大鼠衰老进程。
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Nutritional influences on aging of Fischer 344 rats: I. Physical, metabolic, and longevity characteristics.营养对Fischer 344大鼠衰老的影响:I. 身体、代谢和寿命特征。
J Gerontol. 1985 Nov;40(6):657-70. doi: 10.1093/geronj/40.6.657.
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