Wood C B, Horne C H, Towler C M, Bohn H, Blumgart L H
Br J Surg. 1978 Sep;65(9):653-6. doi: 10.1002/bjs.1800650919.
Serum pregnancy-associated alpha2-glycoprotein (alpha2PAG) levels have been measured in 67 patients with colorectal cancer. Postoperative changes in alpha2PAG concentrations were observed in patients undergoing apparently curative surgery and compared with results in patients with residual local or metastatic tumour. Significant increase in alpha2PAG levels were found only in those patients with residual or disseminated tumour. In this study alpha2PAG levels closely paralleled the clinical course of the disease in many patients.
对67例结直肠癌患者测定了血清妊娠相关α2-糖蛋白(α2PAG)水平。观察了接受根治性手术患者术后α2PAG浓度的变化,并与有局部残留或转移瘤患者的结果进行比较。仅在那些有残留或播散性肿瘤的患者中发现α2PAG水平显著升高。在本研究中,许多患者的α2PAG水平与疾病的临床进程密切平行。