Krogh B, Jørn Jensen P, Henneberg S W, Hole P, Kronborg O
Department of Anaesthesiology and Intensive Care, Odense University Hospital, Denmark.
Br J Anaesth. 1994 Jan;72(1):55-7. doi: 10.1093/bja/72.1.55.
We studied 150 patients undergoing elective colonic surgery; they were allocated randomly to undergo artificial ventilation with either air-oxygen or nitrous oxide-oxygen during surgery. Eleven patients were excluded. Preoperative management, surgery and postoperative analgesia were similar in both groups. Anaesthesia included propofol by infusion, pancuronium and fentanyl 3 micrograms kg-1 h-1. The air-oxygen group required a continuous infusion of propofol of 4-6 mg kg-1 h-1 whereas the nitrous oxide-oxygen group required only 1-2 mg kg-1 h-1. There were no differences between the groups in duration of anaesthesia, distension of the bowel and postoperative bowel function. The postoperative hospital stay was similar for both groups.
我们研究了150例行择期结肠手术的患者；他们被随机分配在手术期间接受空气-氧气或氧化亚氮-氧气人工通气。11名患者被排除。两组患者的术前管理、手术及术后镇痛相似。麻醉包括丙泊酚静脉输注、泮库溴铵及芬太尼3微克·千克⁻¹·小时⁻¹。空气-氧气组需要4-6毫克·千克⁻¹·小时⁻¹的丙泊酚持续输注，而氧化亚氮-氧气组仅需要1-2毫克·千克⁻¹·小时⁻¹。两组在麻醉持续时间、肠扩张及术后肠功能方面无差异。两组患者的术后住院时间相似。
