Pereponov Iu P, Belova E V, Lil'in E T
Kardiologiia. 1993;33(8):28-31.
Twenty-eight pairs of unisexual healthy twins were examined during exercise, on anapriline or their combination. The twin technique of calculating the additive component of blood pressure and catecholamine levels was used in each of the terms of the examination. beta-adrenoceptor blockade was found to be a highly potent environmental factor under whose influence both resting and exercise blood pressures were not provided by inheritable regulatory mechanisms. The latter resulted in tense synthetic function of the sympathoadrenal system and in disadaptation of the cardiovascular system when anapriline and exercise were used, which might serve an individual prognostic criterion of exercise tolerance.
对28对单性健康双胞胎在运动时、服用心得安或二者联合作用下进行了检查。在检查的每个阶段都采用了双胞胎技术来计算血压和儿茶酚胺水平的加性成分。发现β-肾上腺素能受体阻滞是一个非常强大的环境因素，在其影响下，静息血压和运动血压均不受遗传调节机制的影响。当使用心得安和运动时，后者导致交感肾上腺系统的紧张合成功能以及心血管系统的适应不良，这可能是运动耐力的个体预后标准。
