Katsenovich R A, Kostko S Z, Kozhinskiĭ V M, Kuchenkova M A
Ter Arkh. 1984;56(9):51-3.
The relationship between the effect of propranolol treatment on oxygen consumption during exercise and the activity of the sympathoadrenal system (SAS) and the initial hemodynamic circulatory type was established in patients with coronary heart disease (CHD). In patients with the hyper- and eukinetic circulatory types, propranolol caused an increase in the maximal oxygen consumption (MOC), pointing to the improvement of the functional possibilities of the cardiovascular system during exercise, with this improvement being more marked in patients with the hyperkinetic type. This effect of propranolol in the latter group patients was coupled with a reduction in the transmitter activity of the SAS. In patients with the hypokinetic circulatory type, propranolol did not produce any substantial change in the MOC, modifying the conditions of exercise performance toward anaerobic process without exerting any effect on the SAS.
在冠心病（CHD）患者中，确立了普萘洛尔治疗对运动期间耗氧量的影响与交感肾上腺系统（SAS）活性及初始血流动力学循环类型之间的关系。在高动力型和正常动力型循环类型的患者中，普萘洛尔使最大耗氧量（MOC）增加，这表明运动期间心血管系统的功能能力得到改善，在高动力型患者中这种改善更为明显。普萘洛尔对后一组患者的这种作用与SAS递质活性降低有关。在低动力型循环类型的患者中，普萘洛尔对MOC没有产生任何实质性变化，将运动表现的条件向无氧过程转变，而对SAS没有任何影响。
