饮用水活性炭吸附物在艾姆斯试验中的致突变性。

Mutagenicity of activated carbon adsorbate of drinking water in the Ames assay.

作者信息

Shibuya N, Ohta T, Nakadaira H, Mano H, Endoh K, Yamamoto M

机构信息

Biochemical Laboratory, Niigata College of Medical Technology.

出版信息

Tohoku J Exp Med. 1993 Sep;171(1):89-95. doi: 10.1620/tjem.171.89.

DOI:10.1620/tjem.171.89

PMID:8122259

Abstract

Mutagenicity of activated carbon adsorbate from drinking water collected in Niigata City was assayed by the Ames assay. Adsorbate was extracted from activated carbon with benzene, and then with ethanol. Although the benzene extract was not mutagenic, the ethanol one showed the mutagenic activity for Salmonella typhimurium strains TA98 and TA100 with and without S9 mix. The ethanol extract was much more mutagenic on TA100 than TA98 both with and without S9 mix. The mutagenic activity per liter of water was found to be the strongest in winter and the weakest in summer.

摘要

采用艾姆斯试验法对新潟市采集的饮用水中活性炭吸附物的致突变性进行了测定。用苯从活性炭中提取吸附物，然后再用乙醇提取。虽然苯提取物没有致突变性，但乙醇提取物对鼠伤寒沙门氏菌TA98和TA100菌株在有和没有S9混合液的情况下均表现出致突变活性。无论有无S9混合液，乙醇提取物对TA100的致突变性都比TA98强得多。发现每升水的致突变活性在冬季最强，夏季最弱。