Lubeck D P, Patrick D L, McNulty P, Fifer S K, Birnbaum J
Technology Assessment Group, San Francisco, CA 94107.
Qual Life Res. 1993 Oct;2(5):341-8. doi: 10.1007/BF00449429.
Onychomycosis is a fungal infection of the nails which, although unsightly in appearance, is often considered to be a cosmetic problem. This research reports on the development and performance of a quality-of-life instrument to measure the impact of this disease on the patients' mental and general health, social functioning, pain, and self-confidence. In telephone interviews, 680 members of a health maintenance organization (299 with onychomycosis and 381 without) were asked a battery of items regarding quality of life (mental and social functioning, self-esteem, pain) and specific problems and symptoms related with one's nails. Persons with onychomycosis had significantly poorer ratings compared with the healthy persons with respect to general health (p = 0.02) and bodily pain p < 0.001). Persons with onychomycosis also had significantly (p < 0.05) poorer ratings for mental health, social functioning, health concern, physical appearance, and functional limitations associated with activities involving standing on one's feet or working with one's fingers. This study is the first to document the impact of onychomycosis on an individual's quality of life. Persons with onychomycosis may adapt to this condition, but they continue to experience embarrassment and discomfort that reduces their quality of life.
甲癣是一种指甲真菌感染,尽管外观难看,但通常被认为是一个美容问题。本研究报告了一种生活质量测量工具的开发与性能,该工具用于衡量这种疾病对患者心理和总体健康、社会功能、疼痛及自信心的影响。在电话访谈中,对一个健康维护组织的680名成员(299名患有甲癣,381名未患甲癣)询问了一系列关于生活质量(心理和社会功能、自尊、疼痛)以及与指甲相关的特定问题和症状的项目。与健康人相比,甲癣患者在总体健康方面(p = 0.02)和身体疼痛方面(p < 0.001)的评分明显更低。甲癣患者在心理健康、社会功能、健康担忧、外貌以及与站立或用手指工作相关活动的功能受限方面的评分也明显更低(p < 0.05)。本研究首次记录了甲癣对个人生活质量的影响。甲癣患者可能会适应这种状况,但他们仍会持续感到尴尬和不适,从而降低了生活质量。