• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

毛发分析作为监测和管理美沙酮维持治疗患者的一种工具。讨论。

Hair analysis as a tool for monitoring and managing patients on methadone maintenance. A discussion.

作者信息

Brewer C

机构信息

Stapleford Centre, Belgravia, London, UK.

出版信息

Forensic Sci Int. 1993 Dec;63(1-3):277-83. doi: 10.1016/0379-0738(93)90281-e.

DOI:10.1016/0379-0738(93)90281-e
PMID:8138228
Abstract

Hair analysis for unprescribed drugs is not merely an effective, dignified, and time-saving alternative to urine testing. It is also more sensitive and more difficult to evade and minimises the risk of infection to clinic staff. Because of these characteristics, it can, when properly used, change the nature of the relationship between treatment personnel and patients on methadone maintenance. These changes can be beneficial and acceptable to both parties. In 263 patients, 41% of hair samples were negative for opiates, 22% had levels below 10 ng/10 mg, while in a further 7% the level was less than 20 ng/10 mg. The existing and potential advantages of this technique in managing both opiate abuse and other sorts of drug abuse are discussed.

摘要

对未开具处方药物的毛发分析不仅是一种有效、体面且节省时间的尿液检测替代方法。它还更灵敏、更难规避,并且将对诊所工作人员的感染风险降至最低。由于这些特性,在正确使用时,它可以改变美沙酮维持治疗中治疗人员与患者之间关系的性质。这些变化对双方都有益且可接受。在263名患者中,41%的毛发样本鸦片类药物检测呈阴性,22%的样本含量低于10纳克/10毫克,另有7%的样本含量低于20纳克/10毫克。本文讨论了该技术在管理鸦片类药物滥用和其他类型药物滥用方面现有的和潜在的优势。

相似文献

1
Hair analysis as a tool for monitoring and managing patients on methadone maintenance. A discussion.毛发分析作为监测和管理美沙酮维持治疗患者的一种工具。讨论。
Forensic Sci Int. 1993 Dec;63(1-3):277-83. doi: 10.1016/0379-0738(93)90281-e.
2
Detection of methadone, methadone metabolites, and other illicit drugs of abuse in hair of methadone-treatment subjects.美沙酮治疗对象毛发中美沙酮、美沙酮代谢物及其他滥用非法药物的检测。
J Anal Toxicol. 1998 Oct;22(6):526-30. doi: 10.1093/jat/22.6.526.
3
Simultaneous determination of drugs of abuse (opiates, cocaine and amphetamine) in human hair by GC/MS and its application to a methadone treatment program.气相色谱/质谱联用同时测定人发中滥用药物(阿片类、可卡因和苯丙胺)及其在美沙酮治疗项目中的应用
Forensic Sci Int. 1993 Dec;63(1-3):185-206. doi: 10.1016/0379-0738(93)90273-d.
4
Results of hair analyses for drugs of abuse and comparison with self-reports and urine tests.滥用药物毛发分析结果以及与自我报告和尿液检测的比较。
Forensic Sci Int. 2006 Jan 27;156(2-3):118-23. doi: 10.1016/j.forsciint.2004.07.024.
5
Qualitative screening for drugs of abuse in hair using GC-MS.使用气相色谱 - 质谱联用仪对毛发中的滥用药物进行定性筛查。
J Anal Toxicol. 2001 Apr;25(3):203-8. doi: 10.1093/jat/25.3.203.
6
Interindividual dose/concentration relationship for methadone in hair.头发中美沙酮的个体间剂量/浓度关系。
J Anal Toxicol. 2003 Jan-Feb;27(1):20-3. doi: 10.1093/jat/27.1.20.
7
Methadone and illegal drugs in hair from children with parents in maintenance treatment or suspected for drug abuse in a German community.接受维持治疗的父母的子女的头发中的美沙酮和非法药物,以及德国社区中疑似药物滥用者的子女的头发中的美沙酮和非法药物。
Ther Drug Monit. 2013 Dec;35(6):737-52. doi: 10.1097/FTD.0b013e31829a78c3.
8
Radioimmunoassay of drugs of abuse in hair. Part 2: The determination of methadone in the hair of known drug users.毛发中滥用药物的放射免疫分析。第2部分:已知吸毒者毛发中美沙酮的测定。
J Pharm Biomed Anal. 1995 Jun;13(7):829-39. doi: 10.1016/0731-7085(95)01517-o.
9
Methadone in hair and sweat from patients in long-term maintenance therapy.长期维持治疗患者头发和汗液中的美沙酮。
Ther Drug Monit. 2007 Aug;29(4):452-4. doi: 10.1097/FTD.0b013e31811f1bbe.
10
Comparison of Cozart microplate ELISA and GC-MS detection of methadone and metabolites in human hair.考扎特酶标板酶联免疫吸附测定法与气相色谱-质谱联用检测人发中美沙酮及其代谢物的比较
J Anal Toxicol. 2005 Oct;29(7):678-81. doi: 10.1093/jat/29.7.678.

引用本文的文献

1
Recent developments in maintenance prescribing and monitoring in the United Kingdom.英国维持性处方及监测的最新进展。
Bull N Y Acad Med. 1995 Winter;72(2):359-70.
2
Methadone treatment. Clinical judgment is important.美沙酮治疗。临床判断很重要。
BMJ. 1996 Dec 7;313(7070):1482. doi: 10.1136/bmj.313.7070.1482.