Cayton H R, Osborne A D, Sylvester D G
Vet Rec. 1975 Dec 6;97(23):447-9.
Serial Brucella agglutination tests were carried out on veterinary students at Bristol University between 1962 and 1968. A steady rise in the number of those with a significant positive titre was demonstrated in undergraduates and this was related to an increased exposure to farm livestock as their course progressed. A much larger proportion of individuals showed a significant titre in the period following graduation. While only 8-9 per cent of students in the first year of their course showed a significant titre, 49-5 per cent gave a serological response at 1/80 dilution or greater, within five years ofgraduation and of those in predominantly large animal practice almost 60 per cent showed this response. Only 7 per cent of those with a significant rise in titre reported symptoms suggestive of clinical disease.
1962年至1968年间，对布里斯托大学的兽医专业学生进行了布鲁氏菌凝集试验。结果显示，随着课程的推进，本科生中凝集效价呈显著阳性的人数稳步上升，这与他们更多地接触农场牲畜有关。毕业后有更大比例的人凝集效价呈显著阳性。在课程第一年只有8%至9%的学生凝集效价呈显著阳性，而在毕业五年内，49%至5%的学生在1/80稀释度或更高稀释度时出现血清学反应，在主要从事大型动物诊疗工作的学生中，近60%出现了这种反应。凝集效价显著升高的人中只有7%报告有临床疾病的症状。
