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肝内脏幼虫移行症:病变的演变、诊断及高剂量阿苯达唑治疗的作用

Hepatic visceral larva migrans: evolution of the lesion, diagnosis, and role of high-dose albendazole therapy.

作者信息

Bhatia V, Sarin S K

机构信息

Department of Gastroenterology, G.B. Pant Hospital, New Delhi, India.

出版信息

Am J Gastroenterol. 1994 Apr;89(4):624-7.

PMID:8147371
Abstract

An unusual presentation of hepatic involvement of visceral larva migrans is described. A 45-yr-old male presented with fever, pain in the right upper quadrant, and persistent eosinophilia. Ultrasound initially detected a solitary hypoechoic area in the right lobe of the liver which rapidly progressed to multiple lesions with peripheral hyperechoic lesions. Aspiration from the lesion revealed Charcot-Leyden crystals and sheets of eosinophils. Serology for Toxocara canis was strongly positive. Prolonged and high-dose albendazole therapy, in combination with antibiotics, was required to treat the patient effectively.

摘要

本文描述了内脏幼虫移行症肝脏受累的一种不寻常表现。一名45岁男性患者出现发热、右上腹疼痛和持续性嗜酸性粒细胞增多。超声最初在肝脏右叶检测到一个孤立的低回声区,该区域迅速发展为多个病灶,并伴有周边高回声病灶。病灶穿刺抽吸物中发现夏科-莱登结晶和大量嗜酸性粒细胞。犬弓首线虫血清学检测呈强阳性。需要长期、高剂量的阿苯达唑治疗并联合使用抗生素才能有效治疗该患者。

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