Kaw M, Sekas G
Division of Gastroenterology and Hepatology, University of Pittsburgh School of Medicine, Pennsylvania 15213.
Dig Dis Sci. 1994 Apr;39(4):738-43. doi: 10.1007/BF02087416.
PEG (percutaneous endoscopic gastrostomy) tubes are frequently placed in nursing home patients. The aim of this study was to assess retrospectively the long-term changes in functional and nutritional statuses, tube-related complications, and factors influencing survival in 46 nursing home residents, mean age 73.6 years (range 19-96). Functional status was evaluated by a standard rehabilitation medicine scale. Nutritional status was evaluated by serum albumin and cholesterol concentrations and by weight. PEG-related complications requiring hospitalization or emergency room or clinic evaluations were noted. Additionally, changes in resuscitation status were noted. The predominant indication for PEG placement was dementia (52%). At PEG placement, 48% of patients had total functional impairment. Regardless of the severity of impairment, no patient's functional status improved after PEG. Nutritional status did not improve significantly. Mortality approached 50% and 60% at 12 and 18 months, respectively, and was significantly related to age, resuscitation status, and serum albumin concentration. All patients under 40 years of age at PEG survived, in contrast to 41.3% of patients over 40 years of age (P < 0.001). Sixty-three percent of patients who were "full code" at PEG placement survived, in contrast to 10% of "no code" patients (P < 0.001). Albumin > or = 3.5 g/dl at PEG or thereafter was associated with improved survival (P < 0.001) as compared to albumin < 3.5 g/dl. PEG-related complications occurred in 34.7% of patients, and the first occurred four months after PEG. We conclude that realistic expectations of what PEG can accomplish be a factor in the decision to place a PEG tube in nursing home patients.
经皮内镜下胃造口术(PEG)管常用于养老院患者。本研究旨在回顾性评估46例平均年龄73.6岁(范围19 - 96岁)的养老院居民的功能和营养状况的长期变化、与置管相关的并发症以及影响生存的因素。功能状况通过标准康复医学量表进行评估。营养状况通过血清白蛋白和胆固醇浓度以及体重进行评估。记录需要住院治疗或到急诊室或诊所评估的与PEG相关的并发症。此外,还记录了复苏状态的变化。PEG置管的主要指征是痴呆(52%)。在PEG置管时,48%的患者存在完全功能障碍。无论功能障碍的严重程度如何,PEG置管后没有患者的功能状况得到改善。营养状况也没有显著改善。12个月和18个月时的死亡率分别接近50%和60%,且与年龄、复苏状态和血清白蛋白浓度显著相关。PEG置管时年龄在40岁以下的所有患者均存活,而40岁以上的患者存活率为41.3%(P < 0.001)。PEG置管时“完全复苏”的患者中有63%存活,而“不进行复苏”的患者存活率为10%(P < 0.001)与白蛋白< 3.5 g/dl相比,PEG置管时或之后白蛋白≥3.5 g/dl与生存率提高相关(P < 0.001)。34.7%的患者发生了与PEG相关的并发症,首次并发症发生在PEG置管后4个月。我们得出结论,对PEG所能达到的效果有现实的期望是决定是否为养老院患者置入PEG管的一个因素。