Hatzitheoklitos E, Büchler M W, Friess H, Poch B, Ebert M, Mohr W, Imaizumi T, Beger H G
Department of Visceral and Transplantation Surgery, University of Berne, Switzerland.
Cancer. 1994 Mar 15;73(6):1580-8. doi: 10.1002/1097-0142(19940315)73:6<1580::aid-cncr2820730608>3.0.co;2-0.
Carcinoid tumors of the gastrointestinal tract are most common localized in the appendix, followed by the small intestine, the rectum, and the stomach. The localization of these tumors at the ampulla of Vater is extremely seldom.
In the present study the authors describe two patients with carcinoid tumors of the ampulla Vater and review 71 previously published cases.
Most patients presented with jaundice, but without carcinoid syndrome. Because the tumor grows submucosally, preoperative diagnosis was correct only in 15%. Most tumors were around 2 cm in size. Metastasis to lymph nodes and/or liver was present in 45%. Standard treatment is Whipple resection or local excision in small tumors.
Carcinoid tumors of the ampulla of Vater are an extremely rare clinical entity. Generally, the prognosis is good with a 5-year survival period of 90%.
胃肠道类癌肿瘤最常见于阑尾，其次是小肠、直肠和胃。这些肿瘤位于 Vater 壶腹的情况极为罕见。
在本研究中，作者描述了两名患有 Vater 壶腹类癌肿瘤的患者，并回顾了 71 例先前发表的病例。
大多数患者出现黄疸，但无类癌综合征。由于肿瘤在黏膜下层生长，术前诊断的正确率仅为 15%。大多数肿瘤大小约为 2 cm。45%的患者出现淋巴结和/或肝脏转移。标准治疗方法是 Whipple 切除术或对小肿瘤进行局部切除。
Vater 壶腹类癌肿瘤是一种极为罕见的临床实体。一般来说，预后良好，5 年生存率为 90%。
