Jakubowski M
Instytutu Medycyny Pracy, Lodzi.
Med Pr. 1993;44(6 Suppl 1):15-34.
The author discussed current data on sources of the environmental exposure to lead, health effects of exposure in adults and children as well as recommended admissible concentrations of lead in blood. The review of studies on biological monitoring of exposure to lead in Poland permits to state that the results of measurements of Pb-B concentrations performed by laboratories which did not participate in the inter-laboratory programme of quality assurance were often overestimated evoking public concern. The outcome of investigations carried out by the Nofer Institute of Occupational Medicine in Lodz and other institutions which are provided with appropriate analytical equipment, tested under the inter-laboratory programme of quality assurance gives the ground for a hypothesis that an excessive environmental exposure to lead in Poland may result only from industrial emission. The mean geometric lead blood concentrations in persons living in areas free from industrial emissions of lead range from 40 to 70 micrograms/l and they do not prove any potential hazard for adults. Exposure of children and pregnant women living in areas polluted with lead due to industrial emissions and where mean geometric Pb-B concentrations reach 100-170 micrograms/l may create a significant problem. The results obtained emphasize the need for targetted surveillance aimed at identifying areas of excessive lead contamination, measurements of Pb-B concentrations in populations living in those areas and necessary preventive measurements. Collection of blood samples and measurements of lead levels should be performed only by those laboratories which satisfy necessary requirements.
作者讨论了有关环境铅暴露源的现有数据、成人和儿童铅暴露的健康影响以及推荐的血铅容许浓度。对波兰铅暴露生物监测研究的综述表明,未参与实验室间质量保证计划的实验室所进行的血铅(Pb-B)浓度测量结果往往被高估,这引起了公众的关注。罗兹的诺费尔职业医学研究所和其他配备了适当分析设备的机构在实验室间质量保证计划下进行的调查结果,为波兰环境铅过度暴露可能仅源于工业排放这一假设提供了依据。生活在无铅工业排放地区的人群的平均几何血铅浓度在40至70微克/升之间,这并未证明对成年人有任何潜在危害。生活在因工业排放而铅污染地区的儿童和孕妇,其平均几何血铅浓度达到100 - 170微克/升,可能会产生严重问题。所获得的结果强调了进行有针对性监测的必要性,旨在确定铅污染超标区域、测量生活在这些区域人群的血铅浓度以及采取必要的预防措施。血样采集和铅水平测量仅应由满足必要要求的实验室进行。