Brink S, Cloete H, Roberts R, Holm W
S Afr Med J. 1976 Feb 14;50(7):205-8.
Standardisation and quality control are now available for the laboratory tests which are needed to control the blood levels of anticoagulants. The most important cause for variation in results between different laboratories is the use of different types of thromboplastin. The British standards are based on the use of a national reagent with a national system of reporting supported by quality control with lyophilised plasma and thromboplastin preparations. It offers a model which has been adopted at Tygerberg Hospital, and could be used to standardise anticoagulant therapy in this country. Human brain thromboplastin is preferred to the commercially available rabbit preparations. For the first time, as far as we know, a phenol-saline extract of baboon brain thromboplastin was examined. Preliminary results indicate that it compares well with human brain extracts.
目前，用于控制抗凝剂血液水平的实验室检测已有标准化和质量控制措施。不同实验室结果存在差异的最重要原因是使用了不同类型的凝血活酶。英国的标准基于使用一种国家试剂，并采用国家报告系统，该系统由冻干血浆和凝血活酶制剂的质量控制提供支持。它提供了一个已被泰格堡医院采用的模式，可用于该国抗凝治疗的标准化。人脑凝血活酶比市售的兔凝血活酶制剂更受青睐。据我们所知，首次对狒狒脑凝血活酶的酚盐提取物进行了检测。初步结果表明，它与人类脑提取物相比效果良好。
