老年人营养性叶酸缺乏时叶酸的可逆性吸收不良。

Reversible malabsorption of folic acid in the elderly with nutritional folate deficiency.

作者信息

Elsborg L

出版信息

Acta Haematol. 1976;55(3):140-7. doi: 10.1159/000208006.

DOI:10.1159/000208006

Abstract

In normal subjects, the folic acid absorption (TRIFA test) was independent of age and sex. Among 53 geriatric patients with nutritional folate deficiency, impaired absorption of folic acid was present in 19 (36%). After treatment with folic acid for 4 weeks, the absorption returned to normal. It is concluded that folate deficiency per se can produce a malabsorption syndrome resulting in further depletion of folate. Protein deficiency and weight loss alone do not impair the absorption of folic acid.

摘要

在正常受试者中，叶酸吸收（TRIFA试验）与年龄和性别无关。在53例患有营养性叶酸缺乏的老年患者中，19例（36%）存在叶酸吸收受损。用叶酸治疗4周后，吸收恢复正常。结论是，叶酸缺乏本身可产生吸收不良综合征，导致叶酸进一步耗竭。单纯蛋白质缺乏和体重减轻不会损害叶酸的吸收。