Ritschel W A, Forusz H
Division of Pharmaceutics and Drug Delivery Systems, University of Cincinnati Medical Center, OH 45267.
Methods Find Exp Clin Pharmacol. 1994 Jan-Feb;16(1):57-75.
The science dealing with the phenomenon of rhythmicity in living organisms is called chronobiology. The branch dealing with the pharmacologic aspects of chronobiology is termed chronopharmacology, which may be subdivided into chronotherapy, chronopharmacokinetics and chronotoxicity. After a short discussion of the terminology used in chronobiology, a survey of drugs studied with respect to chronopharmacology, particularly of chronopharmacokinetics in man, is given.
研究生物体内节律性现象的科学称为时间生物学。研究时间生物学药理学方面的分支称为时间药理学,它可细分为时间治疗学、时间药代动力学和时间毒性学。在简短讨论了时间生物学中使用的术语后,本文对在时间药理学方面,特别是在人体时间药代动力学方面所研究的药物进行了综述。