Gaudric A, Fardeau C, Goberville M, Cohen D, Paques M, Mikol J
Service d'ophtalmologie, Hôpital Lariboisière, Université Paris-VII.
J Fr Ophtalmol. 1993;16(11):571-6.
The files of 40 patients operated on for epimacular membranes were reviewed in order to correlate the functional and anatomical results with the presence or absence of internal limiting membrane on histological specimens. Only the eyes with idiopathic membranes were considered for the study. Visual acuity and fluorescein angiography were obtained preoperatively and at the 6 months postoperative visit. The surface of the posterior pole was measured on fluorescein angiogram pre and postoperatively by computerized image analysis. Light microscopy looked for the presence of significant segments of internal limiting membrane. In 28 cases (group 1) long segments of internal limiting membrane were adherent to the epimacular membrane and in 12 cases (group 2) no internal limiting membrane fragments or only small fragments were present. Mean postoperative visual acuity was the same in the two groups; 64% of eyes from group I and 50% from group 2 had visual acuity superior or equal to 0.5 (NS). Image analysis showed that the posterior pole surface area increased by 25% in group 1 but only by 15% in group 2 (p < 0.025). Internal limiting membrane ablation does not preclude good visual recovery and is correlated with improved unfolding of the posterior pole.
回顾了40例行黄斑前膜手术患者的病历，以便将功能和解剖学结果与组织学标本中有无内界膜相关联。本研究仅纳入患有特发性黄斑前膜的患眼。术前及术后6个月时记录视力和荧光素血管造影结果。通过计算机图像分析测量术前及术后荧光素血管造影图像上后极部的表面积。光学显微镜检查内界膜的显著节段。28例（第1组）内界膜的长节段附着于黄斑前膜，12例（第2组）未发现内界膜碎片或仅存在小碎片。两组术后平均视力相同；第1组64%的患眼和第2组50%的患眼视力优于或等于0.5（无统计学差异）。图像分析显示，第1组后极部表面积增加25%，而第2组仅增加15%（p<0.025）。内界膜剥除并不妨碍良好的视力恢复，且与后极部更好的展开相关。
