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霍乱弧菌O139孟加拉型在印度的传播。

Spread of Vibrio cholerae O139 Bengal in India.

作者信息

Nair G B, Ramamurthy T, Bhattacharya S K, Mukhopadhyay A K, Garg S, Bhattacharya M K, Takeda T, Shimada T, Takeda Y, Deb B C

机构信息

National Institute of Cholera and Enteric Diseases (Indian Council of Medical Research), Calcutta.

出版信息

J Infect Dis. 1994 May;169(5):1029-34. doi: 10.1093/infdis/169.5.1029.

DOI:10.1093/infdis/169.5.1029
PMID:8169387
Abstract

Vibrio cholerae serogroup O139 Bengal, a novel strain with epidemic potential, completely displaced V. cholerae serogroup 01 in Calcutta in January 1993, which was followed by an epidemic caused by V. cholerae O139 in March-May 1993. From November 1992 to July 1993, 95.6% of 916 V. cholerae isolates submitted to the National Institute of Cholera and Enteric Diseases from 28 locations in India were confirmed as serogroup O139. As of July 1993, V. cholerae O139 had been isolated from 13 Indian states and a union territory, and large outbreaks of cholera caused by the O139 serogroup had occurred in several cities. The extent of spread of V. cholerae O139 Bengal in India and its ability to swiftly disseminate leaves little doubt that this is the beginning of the eighth pandemic of cholera.

摘要

霍乱弧菌O139孟加拉血清型是一种具有流行潜力的新型菌株,1993年1月在加尔各答它完全取代了霍乱弧菌O1血清型,随后在1993年3月至5月间引发了由O139霍乱弧菌引起的疫情。从1992年11月到1993年7月,从印度28个地点提交给国家霍乱和肠道疾病研究所的916株霍乱弧菌分离株中,95.6%被确认为O139血清型。截至1993年7月,O139霍乱弧菌已在印度的13个邦和一个中央直辖区被分离出来,并且由O139血清型引起的霍乱大爆发已在几个城市发生。O139孟加拉霍乱弧菌在印度的传播范围及其迅速传播的能力毫无疑问地表明,这是霍乱第八次大流行的开端。

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