Perlman J I, Urban R C, Edward D P, Tso M O
Georgiana Dvorak Theobald Ophthalmic Pathology Laboratory, Department of Ophthalmology and Visual Sciences, Lions of Illinois Eye Research Institute, University of Illinois at Chicago College of Medicine 60612.
Am J Ophthalmol. 1994 May 15;117(5):647-50. doi: 10.1016/s0002-9394(14)70072-8.
Syringocystadenoma papilliferum is a benign adnexal tumor of the scalp and face. We treated syringocystadenoma papilliferum in a 31-year-old man who had a circumscribed cup-shaped lesion of the left upper eyelid with a central crater. On histologic examination, the epidermal edge showed hyperkeratosis and invasive acanthosis with papillary projections that filled the central crater. The deeper portions of the projections resembled ductal structures lined by an inner columnar epithelium, which demonstrated luminal apical decapitation secretions, and an outer layer of smaller cuboidal cells. The fibrovascular dermal tissue exhibited prominent plasmacytic infiltration underlying the papillary epithelium. Although rare, syringocystadenoma papilliferum should be considered in the differential diagnosis of umbilicated squamous or basal cell tumors, especially if noted in a young individual.
乳头状汗管囊腺瘤是一种发生于头皮和面部的良性附属器肿瘤。我们对一名31岁男性的乳头状汗管囊腺瘤进行了治疗，该患者左上睑有一个边界清晰的杯状病变，中央有一个火山口。组织学检查显示，表皮边缘有角化过度和浸润性棘皮症，伴有乳头状突起，填充了中央火山口。突起的深部类似于由内层柱状上皮内衬的导管结构，显示管腔顶端断头分泌，外层为较小的立方细胞。乳头上皮下方的纤维血管性真皮组织有显著的浆细胞浸润。尽管罕见，但在脐状鳞状或基底细胞瘤的鉴别诊断中应考虑乳头状汗管囊腺瘤，尤其是在年轻个体中发现时。
