Hudác A, Palicová F, Geryk B
Výskumný ústav preventívneho lekárstva v Bratislave a Katedra urológie, detskej chirurgie a neurochirurgie LFUK v Bratislave, Slovakia.
Bratisl Lek Listy. 1993 May;94(5):267-71.
The authors present the results of bacteriological analysis of scrapings from the appendical mucosa of 24 rabbits with appendicitis induced by obstruction of the appendix lumen and of 5 rabbits with healthy appendices (controls). In dependence on the duration of inflammation, the recovery of aerobic bacteria was decreasing and that of anaerobic nonsporulating bacteria was increasing. In the group of anaerobic bacteria, gram-negative rods were predominant (number of isolated colonies: 2973 = 79.9%, variation range of occurrence: 10(5)-10(8) per 1 gram of material) with a remarkable prevalence of the genus Bacteroides and particularly of the species Bacteroides fragilis. Compared to the occurrence in appendices with inflammation, the recovery of bacteria in controls was minimal. The work served as model in studying pathogenesis of acute appendicitis in human medicine. (Tab. 3, Ref. 12.)
作者展示了对24只因阑尾腔阻塞诱发阑尾炎的兔子的阑尾黏膜刮片以及5只阑尾健康的兔子（对照组）的阑尾黏膜刮片进行细菌学分析的结果。根据炎症持续时间，需氧菌的回收率在下降，而厌氧无芽孢菌的回收率在上升。在厌氧菌组中，革兰氏阴性杆菌占主导（分离菌落数：2973 = 79.9%，每1克材料的出现变化范围：10(5)-10(8)），拟杆菌属尤其是脆弱拟杆菌的发生率显著。与有炎症的阑尾相比，对照组中细菌的回收率极低。这项研究可作为人类医学中急性阑尾炎发病机制研究的模型。（表3，参考文献12）
