Darr D, Fridovich I
Department of Medicine (Division of Dermatology), Duke University Medical Center, Durham, North Carolina.
J Invest Dermatol. 1994 May;102(5):671-5. doi: 10.1111/1523-1747.ep12374036.
During the past 25 years, the field of free radical biology has germinated, sprouted, and flowered. Free radicals derived from molecular oxygen, formerly of interest only to radiation chemists, are now known to play multiple roles in living systems. We will here consider the generalities of this field with some special focus on skin as a site of oxygen radical production and as a target upon which the damaging propensities of these radicals are exerted.
在过去的25年里，自由基生物学领域已萌芽、生长并蓬勃发展。以前仅为辐射化学家所关注的源自分子氧的自由基，如今已知在生命系统中发挥多种作用。在此，我们将探讨该领域的概况，并特别关注皮肤，它是氧自由基产生的场所，也是这些自由基发挥破坏作用的靶点。
