Department of Clinical Epidemiology, University of London.
Br J Gen Pract. 1994 Feb;44(379):62-7.
The aim of this paper is to describe the prevalence of cardiovascular risk factors in families screened systematically by nurses in British general practice, and in subgroups with reported hypertension, hypercholesterolaemia, diabetes and coronary heart disease.
Twenty six general practices (13 intervention and 13 control practices) in 13 towns in England, Wales and Scotland were involved in a randomized control trial. Randomly ordered invitations were sent for a family health check to 4158 households (men aged 40-59 years and their partners) registered with the 13 intervention practices.
One or more adult members from 2373 households (57%) were screened; in 1477 visits the selected man and his female partner attended of whom 98% were married. In all, 3850 individuals were screened (2246 men and 1604 women); 15% of men and women were in the predefined top quintile of the British family heart study risk score. Twenty four per cent of men and 22% of women smoked cigarettes and 62% of men and 44% of women were overweight (body mass index 25+). One third of men and one sixth of women with no known history of high blood pressure had a diastolic blood pressure of 90+ mmHg. Among the 491 individuals with previously reported high blood pressure 64% were not adequately controlled, having a diastolic blood pressure of 90+ mmHg, while 26% had diastolic blood pressure of 100+ mmHg. Eighteen per cent of men and women with no known history of a high cholesterol level had a random cholesterol level of 6.5+ mmol l-1. In the 173 people with a previously reported high cholesterol level and who had their level measured over half had a cholesterol level of 6.5+ mmol l-1 and in 7% this level was 8.0+ mmol l-1. One per cent of men and 0.3% of women were newly identified as diabetic (random glucose level of 10.0+ mmol l-1). In the 52 with previously diagnosed diabetes unsatisfactory control was found in 52% (random level of 10.0+ mmol l-1). A total of 3034 men and women overall (79%) qualified for follow up for one or more risk factor; 1909 men (85%) and 1125 women (70%). Among the 139 with pre-existing coronary heart disease 119 (86%) had modifiable risk factors: 27% were cigarette smokers, 68% had a body mass index of 25+, 40% had diastolic hypertension, 29% had hypercholesterolaemia and 19% had hyperglycaemia. Five per cent of men and women were taking antihypertensive drugs, 0.3% cholesterol lowering drugs and 0.7% drugs for diabetes.
There is considerable scope for primary and secondary prevention among families registered with general practices, but whether nursing and medical intervention can reduce the risk factors related to cardiovascular disease in this setting remains unknown.
本文旨在描述在英国全科医疗中由护士系统筛查的家庭以及报告患有高血压、高胆固醇血症、糖尿病和冠心病的亚组中心血管危险因素的患病率。
英格兰、威尔士和苏格兰13个城镇的26家全科诊所(13家干预诊所和13家对照诊所)参与了一项随机对照试验。向在13家干预诊所注册的4158户家庭(年龄在40 - 59岁的男性及其伴侣)随机发送家庭健康检查邀请。
2373户家庭(57%)的一名或多名成年成员接受了筛查;在1477次就诊中,选定的男性及其女性伴侣前来就诊,其中98%已婚。总共筛查了3850人(2246名男性和1604名女性);15%的男性和女性处于英国家庭心脏研究风险评分预先定义的最高五分位数。24%的男性和22%的女性吸烟,62%的男性和44%的女性超重(体重指数≥25)。在无高血压病史的男性中,三分之一和女性中六分之一的舒张压≥90 mmHg。在先前报告患有高血压的491人中,64%控制不佳,舒张压≥90 mmHg,而26%的人舒张压≥100 mmHg。在无高胆固醇血症病史的男性和女性中,18%的人随机胆固醇水平≥6.5 mmol/L。在先前报告患有高胆固醇血症且进行了胆固醇水平测量的173人中,超过一半的人胆固醇水平≥6.5 mmol/L,7%的人该水平≥8.0 mmol/L。1%的男性和0.3%的女性被新诊断为糖尿病(随机血糖水平≥10.0 mmol/L)。在先前诊断为糖尿病的52人中,52%控制不佳(随机血糖水平≥10.0 mmol/L)。总共3034名男性和女性(79%)有一个或多个危险因素符合随访条件;1909名男性(85%)和1125名女性(70%)。在139名已有冠心病的患者中,119名(86%)有可改变的危险因素:27%吸烟,68%体重指数≥25,40%有舒张期高血压,29%有高胆固醇血症,19%有高血糖症。5%的男性和女性正在服用抗高血压药物,0.3%服用降胆固醇药物,0.7%服用糖尿病药物。
在全科诊所注册的家庭中,一级和二级预防有很大空间,但在这种情况下,护理和医疗干预能否降低与心血管疾病相关危险因素尚不清楚。