儿童随机尿样中δ-氨基乙酰丙酸排泄情况的评估。
Evaluation of delta-aminolaevulinic acid excretion in random urine samples of children.
作者信息
Hudák A, Kiss G, Náray M, Süveges E
机构信息
Department of Analytical and Clinical Chemistry, National Institute of Occupational Health, Budapest, Hungary.
出版信息
Eur J Pediatr. 1994 Mar;153(3):187-9. doi: 10.1007/BF01958983.
Urinary delta-aminolaevulinic acid (delta-ALA) excretion was evaluated in random urine samples of 191 healthy children, aged 2-14 years, with blood lead levels < 0.8 mumol/l (mean +/- SD: 0.34 +/- 0.13), erythrocyte zinc-protoporphyrin < 70 mumol/mol haem (mean +/- SD: 50.4 +/- 8.0) and blood haemoglobin > 6.8 mmol/l (mean +/- SD: 8.2 +/- 0.5). It was found that uncorrected delta-ALA concentration and delta-ALA/creatinine ratio are age-dependent, whereas the ratio of delta-ALA/logarithm of creatinine concentration (mean +/- SD: 55.3 +/- 13.5 mumol/log mmol) is independent of age and sex. The authors recommend the use of this parameter for the assessment of delta-ALA excretion in random urine samples in children.
对191名2至14岁的健康儿童随机尿样中的尿δ-氨基乙酰丙酸（δ-ALA）排泄情况进行了评估，这些儿童的血铅水平<0.8μmol/l（均值±标准差：0.34±0.13），红细胞锌原卟啉<70μmol/mol血红蛋白（均值±标准差：50.4±8.0），血血红蛋白>6.8mmol/l（均值±标准差：8.2±0.5）。结果发现，未校正的δ-ALA浓度和δ-ALA/肌酐比值与年龄有关，而δ-ALA/肌酐浓度对数的比值（均值±标准差：55.3±13.5μmol/log mmol）与年龄和性别无关。作者建议使用该参数评估儿童随机尿样中的δ-ALA排泄情况。
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