尿量对尿中铅、δ-氨基乙酰丙酸、粪卟啉、肌酐和总溶质浓度的影响。
Effects of urinary volume on urinary concentrations of lead, delta-aminolaevulinic acid, coproporphyrin, creatinine, and total solutes.
作者信息
Araki S
出版信息
Br J Ind Med. 1980 Feb;37(1):50-4. doi: 10.1136/oem.37.1.50.
Urinary volume was related to urinary concentrations of lead, delta-aminolaevulinic acid (ALA), coproporphyrin (COPRO), creatinine, and total solutes in nine lead workers. On a log scale, linear relationships were found between urinary volume and the urinary concentrations. There was a certain difference in the extent of the effects of urinary volume on the urinary concentrations. For example, the concentration of creatinine was more affected by urinary volume than those of lead, ALA, and total solutes among the substances examined: similarly, the concentration of COPRO more than that of ALA. An equation was introduced to eliminate the effects of urinary volume on urinary concentrations. The effects of urinary volume on the concentrations adjusted to urinary specific gravity, osmolality, and creatinine are discussed in the light of these findings.
对9名铅作业工人的尿量与尿中铅、δ-氨基乙酰丙酸（ALA）、粪卟啉（COPRO）、肌酐及总溶质浓度之间的关系进行了研究。在对数尺度上，发现尿量与尿浓度之间呈线性关系。尿量对尿浓度的影响程度存在一定差异。例如，在所检测的物质中，肌酐浓度受尿量的影响比铅、ALA和总溶质的浓度更大；同样，COPRO浓度受尿量的影响比ALA浓度更大。引入了一个方程以消除尿量对尿浓度的影响。根据这些研究结果，讨论了尿量对经尿比重、渗透压和肌酐校正后的浓度的影响。
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