Palladino M A, Lerman S P, Thorbecke G J
J Immunol. 1976 Jun;116(6):1673-6.
Transfer of lymphoid cells from agammaglobulinemic donor chickens into 3- to 4-week-old irradiated recipients that had been surgically bursectomized at 2 to 3 weeks of age significantly depressed the ability of the antibody-forming apparatus to recover from irradiation. Antibody production to Brucella abortus and sheep erythrocytes remained much below control levels in BX donor-cell recipients of both chicken strains studied (SC and FP). Progressive loss of serum IgM and IgG was observed primarily in the FP strain resulting in complete agammaglobulinemia within 4 to 6 weeks after transfer of BX donor spleen cells. Serial transfer of this phenomenon was demonstrated in the SC strain.
将来自无丙种球蛋白血症供体鸡的淋巴细胞转移到3至4周龄的经辐照受体鸡中，这些受体鸡在2至3周龄时已接受手术切除法氏囊，这显著降低了抗体形成器官从辐射中恢复的能力。在所研究的两种鸡品系（SC和FP）的法氏囊切除供体细胞受体中，针对流产布鲁氏菌和绵羊红细胞的抗体产生仍远低于对照水平。主要在FP品系中观察到血清IgM和IgG的逐渐丧失，在转移法氏囊切除供体脾细胞后4至6周内导致完全无丙种球蛋白血症。在SC品系中证实了这种现象的连续传递。
