老年急性中风患者静脉补液与皮下补液的比较。
A comparison of intravenous and subcutaneous hydration in elderly acute stroke patients.
作者信息
Challiner Y C, Jarrett D, Hayward M J, al-Jubouri M A, Julious S A
机构信息
Department of Elderly Services, Queen Alexandra Hospital, Cosham, Portsmouth, UK.
出版信息
Postgrad Med J. 1994 Mar;70(821):195-7. doi: 10.1136/pgmj.70.821.195.
Abstract
The aim of this study was to compare the effectiveness of subcutaneous and intravenous fluid therapy in hydrating, elderly acute stroke patients. Thirty-four such patients, needing parenteral fluids because of impaired consciousness or dysphagia, were randomly allocated to receive either subcutaneous or intravenous fluids (2 litres of dextrose-saline/24 hours). Serum osmolality was measured before starting fluid therapy (Day 1) and on Days 2 and 3. An analysis of covariance of the osmolalities showed no statistical difference between the two groups (P = 0.12). The total cost of cannulae used over the 3 days for the subcutaneous route was approximately a third of that for the intravenous route. Complication rates were similar for the two groups. The results suggest that subcutaneous fluid therapy is an effective alternative to the intravenous route.
摘要
本研究的目的是比较皮下补液疗法和静脉补液疗法对老年急性中风患者补液的有效性。34例因意识障碍或吞咽困难而需要肠外补液的此类患者被随机分配接受皮下或静脉补液（2升葡萄糖盐水/24小时）。在开始补液治疗前（第1天）以及第2天和第3天测量血清渗透压。渗透压的协方差分析显示两组之间无统计学差异（P = 0.12）。皮下途径3天使用套管的总成本约为静脉途径的三分之一。两组的并发症发生率相似。结果表明，皮下补液疗法是静脉补液途径的一种有效替代方法。
相似文献
1
A comparison of intravenous and subcutaneous hydration in elderly acute stroke patients.老年急性中风患者静脉补液与皮下补液的比较。
Postgrad Med J. 1994 Mar;70(821):195-7. doi: 10.1136/pgmj.70.821.195.
2
Randomised controlled trial of intravenous maintenance fluids.静脉维持液的随机对照试验
J Paediatr Child Health. 2009 Jan-Feb;45(1-2):9-14. doi: 10.1111/j.1440-1754.2007.01254.x. Epub 2007 Nov 25.
3
A randomized, controlled trial of oral versus intravenous fluids for lowering blood glucose in emergency department patients with hyperglycemia.一项关于口服补液与静脉补液降低急诊科高血糖患者血糖的随机对照试验。
CJEM. 2014 May;16(3):214-9. doi: 10.2310/8000.2013.131082.
4
Subcutaneous fluids in elderly hospital patients with cognitive impairment.
Gerontology. 1996;42(1):36-9. doi: 10.1159/000213768.
5
Prevention of hyponatremia during maintenance intravenous fluid administration: a prospective randomized study of fluid type versus fluid rate.预防维持性静脉输液期间的低钠血症：液体类型与液体速度的前瞻性随机研究。
J Pediatr. 2010 Feb;156(2):313-9.e1-2. doi: 10.1016/j.jpeds.2009.07.059. Epub 2009 Oct 9.
6
Hypodermoclysis: an alternative infusion technique.皮下输液法：一种替代的输注技术。
Am Fam Physician. 2001 Nov 1;64(9):1575-8.
7
Comparison of isotonic and hypotonic intravenous maintenance fluids: a randomized clinical trial.等渗与低渗静脉维持液的比较：一项随机临床试验。
JAMA Pediatr. 2015 May;169(5):445-51. doi: 10.1001/jamapediatrics.2014.3809.
8
Intravenous fluids for reducing the duration of labour in low risk nulliparous women.用于缩短低风险初产妇产程的静脉输液。
Cochrane Database Syst Rev. 2013 Jun 18;2013(6):CD007715. doi: 10.1002/14651858.CD007715.pub2.
9
140 mmol/L of sodium versus 77 mmol/L of sodium in maintenance intravenous fluid therapy for children in hospital (PIMS): a randomised controlled double-blind trial.维持性静脉输液治疗住院儿童中 140mmol/L 与 77mmol/L 钠的比较（PIMS）：一项随机对照双盲试验。
Lancet. 2015 Mar 28;385(9974):1190-7. doi: 10.1016/S0140-6736(14)61459-8. Epub 2014 Dec 1.
10
Rehydration with fluid of varying tonicities: effects on fluid regulatory hormones and exercise performance in the heat.使用不同张力的液体进行补液：对热环境下液体调节激素和运动表现的影响。
J Appl Physiol (1985). 2007 May;102(5):1899-905. doi: 10.1152/japplphysiol.00920.2006. Epub 2007 Feb 22.
引用本文的文献
1
Subcutaneous hydration and medications infusions (effectiveness, safety, acceptability): A systematic review of systematic reviews.皮下补液和药物输注（有效性、安全性、可接受性）：系统评价的系统评价。
PLoS One. 2020 Aug 24;15(8):e0237572. doi: 10.1371/journal.pone.0237572. eCollection 2020.
2
Pilot study on the effect of subcutaneous administration of lactated Ringer's solution on biochemistry parameters in healthy euvolemic cats.皮下注射乳酸林格氏液对健康血容量正常猫生化参数影响的初步研究。
Vet Med Sci. 2016 Jan 18;2(1):47-53. doi: 10.1002/vms3.19. eCollection 2016 Feb.
3
Subcutaneous injection-induced cellulites.皮下注射引起的蜂窝织炎。
Biomedicine (Taipei). 2017 Jun;7(2):14. doi: 10.1051/bmdcn/2017070206. Epub 2017 Jun 14.
4
Parenteral fluid regimens for improving functional outcome in people with acute stroke.用于改善急性中风患者功能结局的肠外补液方案。
Cochrane Database Syst Rev. 2015 Sep 1;2015(9):CD011138. doi: 10.1002/14651858.CD011138.pub2.
5
Comparison of routes for achieving parenteral access with a focus on the management of patients with Ebola virus disease.实现肠外通路的途径比较，重点关注埃博拉病毒病患者的管理。
Cochrane Database Syst Rev. 2015 Feb 26;2015(2):CD011386. doi: 10.1002/14651858.CD011386.pub2.
6
Intravenous versus Subcutaneous Drug Administration. Which Do Patients Prefer? A Systematic Review.静脉注射与皮下给药。患者更喜欢哪种？一项系统评价。
Patient. 2014 Jul 12. doi: 10.1007/s40271-014-0075-y.
7
Comparison of the tolerability of recombinant human hyaluronidase + normal saline and recombinant human hyaluronidase + lactated ringer's solution administered subcutaneously: A phase IV, double-blind, randomized pilot study in healthy volunteers.皮下注射重组人透明质酸酶+生理盐水与重组人透明质酸酶+乳酸林格氏液的耐受性比较：一项针对健康志愿者的IV期、双盲、随机试点研究。
Curr Ther Res Clin Exp. 2009 Dec;70(6):421-38. doi: 10.1016/j.curtheres.2009.12.005.
8
Guideline clinical nutrition in patients with stroke.中风患者的临床营养指南。
Exp Transl Stroke Med. 2013 Dec 1;5(1):14. doi: 10.1186/2040-7378-5-14.
9
Intravenous therapy.静脉治疗。
Postgrad Med J. 2004 Jan;80(939):1-6. doi: 10.1136/pmj.2003.010421.
10
Subcutaneous hydration by hypodermoclysis. A practical and low cost treatment for elderly patients.皮下输液法进行皮下补液。一种针对老年患者的实用且低成本的治疗方法。
Drugs Aging. 2000 Apr;16(4):313-9. doi: 10.2165/00002512-200016040-00007.
本文引用的文献
1
Hyaluronidase in paediatric therapy.透明质酸酶在儿科治疗中的应用。
Lancet. 1949 Sep 17;2(6577):505-7.
2
The danger of administering parenteral fluids by hypodermoclysis.
Surgery. 1952 Aug;32(2):305-15.
3
Subcutaneous infusions in the elderly.
J Am Geriatr Soc. 1981 Dec;29(12):583-5. doi: 10.1111/j.1532-5415.1981.tb01265.x.
4
Hypodermoclysis revisited.皮下输液法再探讨。
JAMA. 1982 Sep 17;248(11):1310-1. doi: 10.1001/jama.1982.03330110018015.
5
Hypodermoclysis.皮下输液法
JAMA. 1983 Oct 7;250(13):1694-5.
6
Nutrition by hypodermoclysis.皮下输液营养法。
J Am Geriatr Soc. 1984 Mar;32(3):199-203. doi: 10.1111/j.1532-5415.1984.tb02002.x.
7
Influence of age on plasma osmolality: a community study.年龄对血浆渗透压的影响：一项社区研究。
Age Ageing. 1992 Jan;21(1):56-60. doi: 10.1093/ageing/21.1.56.
8
Fluid balance in elderly patients following acute stroke.老年急性脑卒中患者的液体平衡
Age Ageing. 1992 Jul;21(4):280-5. doi: 10.1093/ageing/21.4.280.
9
Hyaluronidase in geriatric therapy.老年治疗中的透明质酸酶。
Practitioner. 1977 Sep;219(1311):361-3.
Zotero 插件