Challiner Y C, Jarrett D, Hayward M J, al-Jubouri M A, Julious S A
Department of Elderly Services, Queen Alexandra Hospital, Cosham, Portsmouth, UK.
Postgrad Med J. 1994 Mar;70(821):195-7. doi: 10.1136/pgmj.70.821.195.
The aim of this study was to compare the effectiveness of subcutaneous and intravenous fluid therapy in hydrating, elderly acute stroke patients. Thirty-four such patients, needing parenteral fluids because of impaired consciousness or dysphagia, were randomly allocated to receive either subcutaneous or intravenous fluids (2 litres of dextrose-saline/24 hours). Serum osmolality was measured before starting fluid therapy (Day 1) and on Days 2 and 3. An analysis of covariance of the osmolalities showed no statistical difference between the two groups (P = 0.12). The total cost of cannulae used over the 3 days for the subcutaneous route was approximately a third of that for the intravenous route. Complication rates were similar for the two groups. The results suggest that subcutaneous fluid therapy is an effective alternative to the intravenous route.
本研究的目的是比较皮下补液疗法和静脉补液疗法对老年急性中风患者补液的有效性。34例因意识障碍或吞咽困难而需要肠外补液的此类患者被随机分配接受皮下或静脉补液（2升葡萄糖盐水/24小时）。在开始补液治疗前（第1天）以及第2天和第3天测量血清渗透压。渗透压的协方差分析显示两组之间无统计学差异（P = 0.12）。皮下途径3天使用套管的总成本约为静脉途径的三分之一。两组的并发症发生率相似。结果表明，皮下补液疗法是静脉补液途径的一种有效替代方法。
