Yamamoto E, Yanagimoto T
Department of Applied Mathematics, Okayama University of Science, Japan.
Environ Health Perspect. 1994 Jan;102 Suppl 1(Suppl 1):25-31. doi: 10.1289/ehp.94102s125.
The beta-binomial model is widely used for analyzing teratological data involving littermates. Recent developments in statistical analyses of teratological data are briefly reviewed with emphasis on the model. For statistical inference of the parameters in the beta-binomial distribution, separation of the likelihood introduces an likelihood inference. This leads to reducing biases of estimators and also to improving accuracy of empirical significance levels of tests. Separate inference of the parameters can be conducted in a unified way.
β-二项式模型广泛用于分析涉及同窝仔畜的畸形学数据。本文简要回顾了畸形学数据统计分析的最新进展，重点是该模型。对于β-二项式分布中参数的统计推断，似然分离引入了似然推断。这导致减少估计量的偏差，并提高检验的经验显著性水平的准确性。参数的单独推断可以以统一的方式进行。
