Miyashita H, Saitho T, Nakano N, Ishigaki H, Ikemoto M, Uthumi K, Watanabe M, Takahata N
Department of Neuropsychiatry, Sapporo Medical University, Japan.
Arukoru Kenkyuto Yakubutsu Ison. 1994 Apr;29(2):114-20.
The case of a chronic alcoholic patient with Wernicke's encephalopathy accompanied by passing blindness is reported and the alcoholic amblyopia is discussed in this study. The patient was a 39 year-old male who had been a heavy drinker for 13 years, and was habitually inebriated for the last one year. Disturbance of consciousness ataxia of gait, nystagmus and blindness were manifested on admission. Decreased level of serum vitamin B1 was also recognized at admission. The symptoms diminished from about a month after admission except for horizontal nystagmus. Since the patient had racket-like scotoma in his central visual field, his blindness was thought to be alcoholic amblyopia. Although alcohol dependence is associated with many physical disabilities, there are few reports about Wernicke's encephalopathy with alcoholic amblyopia. This case demonstrates the importance of careful physical examination for understanding alcohol-related disabilities and alcohol dependence.
本文报告了一例慢性酒精中毒患者,伴有韦尼克脑病并出现一过性失明,同时对酒精性弱视进行了讨论。该患者为39岁男性,有13年的酗酒史,在过去一年中经常醉酒。入院时表现为意识障碍、步态共济失调、眼球震颤和失明。入院时还发现血清维生素B1水平降低。除水平性眼球震颤外,症状在入院后约一个月开始减轻。由于患者中心视野有球拍状暗点,其失明被认为是酒精性弱视。尽管酒精依赖与许多身体残疾有关,但关于韦尼克脑病合并酒精性弱视的报道很少。该病例表明仔细的体格检查对于了解酒精相关残疾和酒精依赖的重要性。