Ito T, Higuchi T, Hirobe M, Hiramatsu K, Yokota T
Department of Bacteriology, School of Medicine, Juntendo University, Tokyo, Japan.
Carbohydr Res. 1994 Mar 18;256(1):113-28. doi: 10.1016/0008-6215(94)84231-0.
A novel sugar in the lipopolysaccharide of Vibrio cholerae O1 serotype Ogawa has been identified. The sugar was liberated from the lipopolysaccharide when hydrolyzed in 10 M HCl at 90 degrees C for 15 min. The sugar was purified and identified as 4-amino-4,6-dideoxy-2-O-methylmannose (2-O-methylperosamine). Since it was found only in the lipopolysaccharide of Vibrio cholerae O1 serotype Ogawa, it seems that the sugar is one of the specific constituents determining Ogawa serotype specificity.
已鉴定出霍乱弧菌小川O1血清型脂多糖中的一种新型糖。该糖在90℃下于10M盐酸中水解15分钟时从脂多糖中释放出来。该糖经纯化后被鉴定为4-氨基-4,6-二脱氧-2-O-甲基甘露糖(2-O-甲基过氧胺)。由于仅在霍乱弧菌小川O1血清型的脂多糖中发现了这种糖,因此该糖似乎是决定小川血清型特异性的特定成分之一。