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对落基山斑疹热的抗体反应

Antibody response to Rocky Mountain spotted fever.

作者信息

Kenyon R H, Canonico P G, Sammons L S, Bagley L R, Pedersen C E

出版信息

J Clin Microbiol. 1976 May;3(5):513-8. doi: 10.1128/jcm.3.5.513-518.1976.

DOI:10.1128/jcm.3.5.513-518.1976
PMID:819455
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC274340/
Abstract

Various techniques were compared to determine the most sensitive method for detection of rocky Mountain spotted fever antibody. A radiometabolic technique for detection of Rocky Mountain spotted fever antibody is also described. In infected monkeys, the fluorescent antibody technique yielded the earliest evidence of seroconversion; with some monkeys the microagglutination procedure was equally effective. The fluorescent antibody and microagglutination measurements showed higher titers than those for complement fixation, Weil-Felix, or the radiometabolic techniques.

摘要

比较了各种技术,以确定检测落基山斑疹热抗体最灵敏的方法。还描述了一种检测落基山斑疹热抗体的放射代谢技术。在受感染的猴子中,荧光抗体技术产生了血清转化的最早证据;对一些猴子来说,微量凝集程序同样有效。荧光抗体和微量凝集测量显示的效价比补体结合、外斐反应或放射代谢技术的效价更高。

相似文献

1
Antibody response to Rocky Mountain spotted fever.对落基山斑疹热的抗体反应
J Clin Microbiol. 1976 May;3(5):513-8. doi: 10.1128/jcm.3.5.513-518.1976.
2
Rocky Mountain spotted fever: a comparative study of the active immunity induced by inactivated and viable pathogenic Rickettsia rickettsii.落基山斑疹热:对灭活和活立克次氏体立克次体诱导的主动免疫的比较研究
J Infect Dis. 1973 Sep;128(3):340-4. doi: 10.1093/infdis/128.3.340.
3
Detection of Rocky Mountain spotted fever antibodies by a latex agglutination test.通过乳胶凝集试验检测落基山斑疹热抗体。
J Clin Microbiol. 1980 Aug;12(2):144-50. doi: 10.1128/jcm.12.2.144-150.1980.
4
Effect of vaccination schedule on immune response of Macaca mulatta to cell culture-grown Rocky Mountain spotted fever vaccine.疫苗接种程序对猕猴针对细胞培养的落基山斑疹热疫苗免疫反应的影响。
J Clin Microbiol. 1976 Sep;4(3):253-7. doi: 10.1128/jcm.4.3.253-257.1976.
5
Discrepancies in Weil-Felix and microimmunofluorescence test results for Rocky Mountain spotted fever.落基山斑疹热的外斐反应和微量免疫荧光试验结果的差异。
J Clin Microbiol. 1979 Feb;9(2):292-3. doi: 10.1128/jcm.9.2.292-293.1979.
6
Humoral immune response to Rocky Mountain spotted fever in experimentally infected guinea pigs: immunoprecipitation of lactoperoxidase 125I-labeled proteins and detection of soluble antigens of Rickettsia rickettsii.实验感染豚鼠对落基山斑疹热的体液免疫反应:乳过氧化物酶125I标记蛋白的免疫沉淀及立氏立克次体可溶性抗原的检测
Infect Immun. 1986 Apr;52(1):120-7. doi: 10.1128/iai.52.1.120-127.1986.
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Evaluation of a killed Rocky Mountain spotted fever vaccine in cynomolgus monkeys.食蟹猴中一种灭活落基山斑疹热疫苗的评估
J Clin Microbiol. 1979 Nov;10(5):719-23. doi: 10.1128/jcm.10.5.719-723.1979.
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Early diagnosis of Rocky Mountain spotted fever. Use of primary monocyte culture technique.落基山斑疹热的早期诊断。原代单核细胞培养技术的应用。
JAMA. 1976 Mar 29;235(13):1353-5.
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Rocky Mountain spotted fever in Mississippi: survey for spotted fever antibodies in dogs and for spotted fever group reckettsiae in dog ticks.密西西比州的落基山斑疹热:犬类斑疹热抗体及犬蜱中斑疹热群立克次体的调查
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Indirect hemagglutination test for human antibody to typhus and spotted fever group rickettsiae.人对斑疹伤寒和斑点热群立克次体抗体的间接血凝试验。
J Clin Microbiol. 1975 Nov;2(5):430-7. doi: 10.1128/jcm.2.5.430-437.1975.

引用本文的文献

1
Immune responses to Rickettsia akari infection in congenitally athymic nude mice.先天性无胸腺裸鼠对小蛛立克次体感染的免疫反应。
Infect Immun. 1980 May;28(2):310-3. doi: 10.1128/iai.28.2.310-313.1980.
2
Effect of vaccination schedule on immune response of Macaca mulatta to cell culture-grown Rocky Mountain spotted fever vaccine.疫苗接种程序对猕猴针对细胞培养的落基山斑疹热疫苗免疫反应的影响。
J Clin Microbiol. 1976 Sep;4(3):253-7. doi: 10.1128/jcm.4.3.253-257.1976.
3
Suppression of cellular immune responses in guinea pigs infected with spotted fever group rickettsiae.感染斑点热群立克次体的豚鼠细胞免疫反应的抑制
Infect Immun. 1978 Nov;22(2):411-7. doi: 10.1128/iai.22.2.411-417.1978.

本文引用的文献

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THE USE OF THE COMPLEMENT FIXATION TEST IN ROCKY MOUNTAIN SPOTTED FEVER.补体结合试验在落基山斑疹热中的应用
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Method for counting Rickettsiae and Chlamydiae in purified suspensions.纯化悬浮液中立克次氏体和衣原体的计数方法。
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Mechanisms of immunity in typhus infections. 3. Influence of human immune serum and complement on the fate of Rickettsia mooseri within the human macrophages.斑疹伤寒感染中的免疫机制。3. 人免疫血清和补体对莫氏立克次体在人巨噬细胞内命运的影响。
Infect Immun. 1973 Oct;8(4):631-40. doi: 10.1128/iai.8.4.631-640.1973.
9
Plaque formation in tissue cultures by Rickettsia rickettsi isolated directly from whole blood and tick hemolymph.从全血和蜱血淋巴中直接分离出的立氏立克次体在组织培养中形成斑块。
Infect Immun. 1972 Nov;6(5):736-8. doi: 10.1128/iai.6.5.736-738.1972.
10
A microagglutination technique for detection and measurement of rickettsial antibodies.一种用于检测和测量立克次氏体抗体的微量凝集技术。
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