Kenyon R H, Canonico P G, Sammons L S, Bagley L R, Pedersen C E
J Clin Microbiol. 1976 May;3(5):513-8. doi: 10.1128/jcm.3.5.513-518.1976.
Various techniques were compared to determine the most sensitive method for detection of rocky Mountain spotted fever antibody. A radiometabolic technique for detection of Rocky Mountain spotted fever antibody is also described. In infected monkeys, the fluorescent antibody technique yielded the earliest evidence of seroconversion; with some monkeys the microagglutination procedure was equally effective. The fluorescent antibody and microagglutination measurements showed higher titers than those for complement fixation, Weil-Felix, or the radiometabolic techniques.
比较了各种技术,以确定检测落基山斑疹热抗体最灵敏的方法。还描述了一种检测落基山斑疹热抗体的放射代谢技术。在受感染的猴子中,荧光抗体技术产生了血清转化的最早证据;对一些猴子来说,微量凝集程序同样有效。荧光抗体和微量凝集测量显示的效价比补体结合、外斐反应或放射代谢技术的效价更高。