Bonner D, Ron M, Chalder T, Butler S, Wessely S
Maudsley Hospital, London, UK.
J Neurol Neurosurg Psychiatry. 1994 May;57(5):617-21. doi: 10.1136/jnnp.57.5.617.
Forty-six of 47 patients diagnosed as having chronic fatigue and offered treatment four years previously were followed up. Twenty-nine patients were interviewed, three patients refused an interview, and information on the remaining 14 was obtained from their general practitioners. All the instruments used at interview had been used in the initial study. The long-term prognosis for patients with chronic fatigue syndrome who have initially responded to treatment is good. Spontaneous recovery in those who declined or who did not benefit from treatment is unlikely. Patients who continue to fulfil the criteria for chronic fatigue syndrome four years after they were initially diagnosed are likely to have had more somatic disorders, to have been more fatigued, and to have had a previous psychiatric history when they were initially assessed.
对47例四年前被诊断为慢性疲劳并接受治疗的患者中的46例进行了随访。29例患者接受了访谈，3例患者拒绝访谈，其余14例患者的信息从他们的全科医生处获得。访谈中使用的所有工具均与初始研究中使用的相同。最初对治疗有反应的慢性疲劳综合征患者的长期预后良好。拒绝治疗或未从治疗中受益的患者不太可能自发康复。最初诊断四年后仍符合慢性疲劳综合征标准的患者，在最初评估时可能有更多躯体疾病、更疲劳且有精神病史。
