Struckmann J R, Nicolaides A N
Department of Gastroenterological Surgery, Herlev University Hospital, Copenhagen, Denmark.
Angiology. 1994 Jun;45(6):419-28. doi: 10.1177/000331979404500602.
Daflon 500 mg consists of 450 mg diosmin and 50 mg flavonoid expressed as hesperidin. The authors describe its effects on the microcirculation in chronic venous insufficiency: improvement of venous tone, inhibition of prostaglandin synthesis, protection against free radicals, activation of the complement system, and increased lymphatic drainage. The authors summarize studies of its therapeutic efficacy in reducing venous capacitance, distensibility, and emptying time; reducing capillary permeability; and increasing capillary resistance.
爱脉朗500毫克含有450毫克地奥司明和以橙皮苷表示的50毫克类黄酮。作者描述了其对慢性静脉功能不全时微循环的影响：改善静脉张力、抑制前列腺素合成、抵御自由基、激活补体系统以及增加淋巴引流。作者总结了关于其治疗效果的研究，包括降低静脉容量、扩张性和排空时间；降低毛细血管通透性；以及增加毛细血管阻力。
