Athanasiou K A, Agarwal A, Dzida F J
Department of Orthopaedics, University of Texas Health Science Center, San Antonio 78284-7774.
J Orthop Res. 1994 May;12(3):340-9. doi: 10.1002/jor.1100120306.
Biphasic creep indentation methodology and an automated indentation apparatus were used to measure the aggregate modulus, Poisson's ratio, permeability, thickness, creep and recovery equilibrium times, and percentage of recovery of normal articular cartilage in 10 human hip joints. These properties were mapped regionally to examine the mechanical factors involved in the development of site-specific degenerative lesions in the acetabulum and femoral head. The results indicate that there are significant differences between these properties regionally in the acetabulum and femoral head and between the two anatomical structures. Specifically, it was found that cartilage in the superomedial aspect of the femoral head has a 41% larger aggregate modulus than its anatomically corresponding articulating surface in the acetabulum. In addition, the superomedial aspect of the femoral head has the greatest aggregate modulus (1.816 MPa) within the hip joint. During sitting, the inferior portion of the femoral head is in contact with the anterior acetabulum, and the anterior acetabulum has a 53% greater aggregate modulus than the inferior femoral head. This area below the fovea on the femoral head has the least aggregate modulus (0.814 MPa) within the hip joint. These mismatches in the compressive modulus of opposing articulating surfaces may contribute to degeneration of cartilage in the superomedial acetabulum and the inferior femoral head. Our findings support the clinical observation that these areas are frequent sites of early degeneration.
采用双相蠕变压痕法和自动压痕装置，对10例人类髋关节正常关节软骨的聚集模量、泊松比、渗透率、厚度、蠕变和恢复平衡时间以及恢复百分比进行了测量。对这些特性进行区域映射，以研究髋臼和股骨头特定部位退行性病变发展过程中的力学因素。结果表明，髋臼和股骨头的这些特性在区域之间以及两个解剖结构之间存在显著差异。具体而言，发现股骨头内上侧的软骨聚集模量比髋臼中与其解剖学对应的关节面大41%。此外，股骨头内上侧在髋关节内具有最大的聚集模量（1.816兆帕）。在坐姿时，股骨头下部与髋臼前部接触，髋臼前部的聚集模量比股骨头下部大53%。股骨头凹部下方的区域在髋关节内具有最小的聚集模量（0.814兆帕）。相对关节面压缩模量的这些不匹配可能导致髋臼内上侧和股骨头下部软骨的退变。我们的研究结果支持了这些区域是早期退变常见部位的临床观察。
