Maresky L S, Grobler S R
Department of Oral Medicine and Periodontics, Faculty of Dentistry, University of Stellenbosch, Tygerberg, South Africa.
Sci Total Environ. 1993 Aug 15;136(1-2):43-8. doi: 10.1016/0048-9697(93)90296-i.
Lead has no metabolic role in the human body and its presence is associated with various toxic effects. Several countries have responded to this health hazard reducing petrol lead additives or entirely eliminating them. Studies have shown that there has been a resultant fall in blood lead levels of the particular populations. This study reports on the progressive decline in blood lead levels of South Africans during the period 1984-1990 which coincided with a stepwise reduction in petrol lead additives from 0.8 g/l to 0.4 g/l. During this period the blood lead levels of Cape Town city dwellers decreased significantly (P < 0.01) from 9.7 micrograms/dl to 7.2 micrograms/dl. This blood lead level compares favourably with that of other more industrialized countries with less lead in their petrol. Therefore, the authors question the need for further reduction of petrol lead content bearing in mind the considerable financial burden that such a step will entail and the dubious health advantage that may be gained.
铅在人体中没有代谢作用,其存在会引发各种毒性效应。一些国家已针对这种健康危害采取措施,减少汽油中的铅添加剂或完全将其消除。研究表明,特定人群的血铅水平因此下降。本研究报告了1984年至1990年期间南非人血铅水平的逐步下降情况,这一时期汽油中的铅添加剂从0.8克/升逐步降至0.4克/升。在此期间,开普敦城市居民的血铅水平从9.7微克/分升显著降至7.2微克/分升(P < 0.01)。这一血铅水平与其他汽油含铅量较低的工业化程度更高的国家相比具有优势。因此,考虑到进一步降低汽油铅含量将带来巨大的经济负担以及可能获得的可疑健康益处,作者对这样做的必要性提出了质疑。