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精神疾病中的血浆和血小板兴奋性氨基酸

Plasma and platelet excitatory amino acids in psychiatric disorders.

作者信息

Altamura C A, Mauri M C, Ferrara A, Moro A R, D'Andrea G, Zamberlan F

机构信息

Department of Clinical Psychiatry, University of Milan School of Medicine, Italy.

出版信息

Am J Psychiatry. 1993 Nov;150(11):1731-3. doi: 10.1176/ajp.150.11.1731.

DOI:10.1176/ajp.150.11.1731
PMID:8214185
Abstract

Plasma and platelet levels of excitatory amino acids were measured in 38 psychiatric out-patients and in 19 comparison subjects; the patients had DSM-III-R diagnoses of organic mental disorders (N = 3), mood disorders (N = 15), schizophrenia (N = 13), and anxiety disorders (N = 7). The glutamate plasma levels were significantly higher in the patients with mood disorders than in the comparison group.

摘要

对38名精神科门诊患者和19名对照受试者的血浆和血小板中兴奋性氨基酸水平进行了测量;这些患者根据《精神疾病诊断与统计手册》第三版修订版(DSM-III-R)被诊断为器质性精神障碍(N = 3)、情绪障碍(N = 15)、精神分裂症(N = 13)和焦虑症(N = 7)。情绪障碍患者的谷氨酸血浆水平显著高于对照组。

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