Whynes D K, Walker A R, Chamberlain J O, Hardcastle J D
Department of Economics, University of Nottingham, UK.
Br J Cancer. 1993 Nov;68(5):965-8. doi: 10.1038/bjc.1993.462.
The objective of this paper is to compare the hospital costs of treating patients with colorectal cancers detected as a result of a faecal occult blood screening programme with those of patients whose cancers present symptomatically (control group). Patient-specific cost estimates are made, using case records and hospital accounts, for 360 patients over 3 years. Mean treatment costs for the group offered screening and for the control group are calculated to be 3,179 pounds and 2,966 pounds respectively, although the difference between these means is insignificant. Low treatment costs in the case of screen-detected cancers are largely accounted for by polypectomy with no subsequent readmission; in the control group case, they tend to be accounted for by early patient death. For the sample as a whole, the costs of treating very early-, and very late-, stage cancer are significantly lower than those of treating cancers in the intermediate stages. On the basis of trial evidence, the introduction of mass screening for colorectal cancer is unlikely to give rise to substantial economies in the costs of treatment.
本文的目的是比较因粪便潜血筛查计划而被检测出患有结直肠癌的患者与出现症状后才被诊断出癌症的患者(对照组)的治疗费用。利用病例记录和医院账目,对360名患者在3年期间的特定患者成本进行了估算。接受筛查组和对照组的平均治疗费用分别计算为3179英镑和2966英镑,尽管这些平均值之间的差异不显著。筛查发现的癌症患者治疗费用较低,主要是因为息肉切除术后未再次入院;而在对照组中,治疗费用较低往往是由于患者早期死亡。对于整个样本而言,极早期和极晚期癌症的治疗费用显著低于中期癌症的治疗费用。基于试验证据,开展结直肠癌大规模筛查不太可能在治疗费用上产生大幅节约。