接触甲基丙烯酸甲酯的工人的支气管症状和呼吸功能
Bronchial symptoms and respiratory function in workers exposed to methylmethacrylate.
作者信息
Marez T, Edmé J L, Boulenguez C, Shirali P, Haguenoer J M
机构信息
Laboratoire de toxicologie, Institut de Médecine du travail-Faculté de Médecine, Lille, France.
出版信息
Br J Ind Med. 1993 Oct;50(10):894-7. doi: 10.1136/oem.50.10.894.
Abstract
This study aimed to investigate the pulmonary effects of methylmethacrylate (MMA) in a group of occupationally exposed workers. In the exposed group 20% had chronic cough compared with 1% in controls. Spirometric values at the beginning of the workshift were similar in both groups, but a mild airways obstruction appeared during the workshift. The maximum expiratory flow when 50% of the forced vital capacity remained to be exhaled (MEF50) and the ratio of MEF50 to maximal expiratory flow (MEF50/MEF) decreased significantly during the workshift among exposed workers v controls (p = 0.04 and 0.01 respectively). Results remained unaffected after adjustment for smoking. Exposure to MMA seems to be responsible for a mild airways obstruction but further study on a larger population would be useful.
摘要
本研究旨在调查甲基丙烯酸甲酯（MMA）对一组职业暴露工人肺部的影响。暴露组中20%的人有慢性咳嗽，而对照组中这一比例为1%。两组在轮班前的肺功能测定值相似，但在轮班期间出现了轻度气道阻塞。暴露工人在轮班期间，呼出50%用力肺活量时的最大呼气流量（MEF50）以及MEF50与最大呼气流量之比（MEF50/MEF）与对照组相比显著降低（分别为p = 0.04和0.01）。在对吸烟进行校正后，结果不受影响。接触MMA似乎是导致轻度气道阻塞的原因，但对更大规模人群进行进一步研究将是有益的。
相似文献
1
Bronchial symptoms and respiratory function in workers exposed to methylmethacrylate.接触甲基丙烯酸甲酯的工人的支气管症状和呼吸功能
Br J Ind Med. 1993 Oct;50(10):894-7. doi: 10.1136/oem.50.10.894.
2
Respiratory symptoms and pulmonary function in flour processing workers in the baking industry.烘焙行业面粉加工工人的呼吸道症状和肺功能
Am J Ind Med. 1995 Mar;27(3):359-65. doi: 10.1002/ajim.4700270305.
3
Respiratory symptoms and ventilatory function in confectionery workers.糖果厂工人的呼吸道症状及通气功能
Occup Environ Med. 1994 Jul;51(7):435-9. doi: 10.1136/oem.51.7.435.
4
Continuous ambulatory electrocardiography among workers exposed to methylmethacrylate.
Int Arch Occup Environ Health. 1992;64(5):373-5. doi: 10.1007/BF00379548.
5
Biomass smoke exposure as an occupational risk: cross-sectional study of respiratory health of women working as street cooks in Nigeria.生物质烟雾暴露作为一种职业风险：对尼日利亚街头女厨师呼吸健康的横断面研究。
Occup Environ Med. 2017 Oct;74(10):737-744. doi: 10.1136/oemed-2016-104107. Epub 2017 Aug 5.
6
Chronic and acute respiratory effects among grain mill workers.谷物加工厂工人的急慢性呼吸道影响。
Int Arch Occup Environ Health. 1995;67(5):311-5. doi: 10.1007/BF00385646.
7
Occupational pesticide exposure and respiratory health: a large-scale cross-sectional study in three commercial farming systems in Ethiopia.职业性农药暴露与呼吸健康：埃塞俄比亚三种商业农业系统中的大规模横断面研究。
Thorax. 2017 Jun;72(6):498-499. doi: 10.1136/thoraxjnl-2016-208924. Epub 2016 Nov 22.
8
Lung function status of some Nigerian men and women chronically exposed to fish drying using burning firewood.一些长期接触用柴火烘干鱼的尼日利亚男性和女性的肺功能状况。
Cent Afr J Med. 1999 May;45(5):119-24. doi: 10.4314/cajm.v45i5.8467.
9
Airway hyperresponsiveness, prevalence of chronic respiratory symptoms, and lung function in workers exposed to irritants.暴露于刺激性物质的工人的气道高反应性、慢性呼吸道症状患病率及肺功能
Occup Environ Med. 1994 Jan;51(1):3-13. doi: 10.1136/oem.51.1.3.
10
Ventilatory functions in cotton textile workers and the role of some inflammatory cytokines.棉纺织工人的通气功能及某些炎性细胞因子的作用
Toxicol Ind Health. 2013 Mar;29(2):114-20. doi: 10.1177/0748233711425071. Epub 2011 Nov 14.
引用本文的文献
1
Micronucleus Assay of Buccal Mucosal Cells in Hairdressers: The Importance of Occupational Exposure.美发师颊黏膜细胞微核试验：职业暴露的重要性
Asian Pac J Cancer Prev. 2018 Aug 24;19(8):2131-2134. doi: 10.22034/APJCP.2018.19.8.2131.
2
Inhalation study of polymethyl methacrylate following radiologist exposure during percutaneous vertebroplasty.经皮椎体成形术放射科医生暴露后聚甲基丙烯酸甲酯吸入研究。
Skeletal Radiol. 2013 Feb;42(2):203-7. doi: 10.1007/s00256-012-1370-0. Epub 2012 Mar 23.
3
Methyl methacrylate and respiratory sensitization: a critical review.甲基丙烯酸甲酯与呼吸道致敏作用：批判性综述。
Crit Rev Toxicol. 2011 Mar;41(3):230-68. doi: 10.3109/10408444.2010.532768.
4
Proportionate cancer mortality in methyl methacrylate-exposed orthopedic surgeons compared to general surgeons.接触 MMA 的矫形外科医生与普通外科医生相比癌症死亡率的比例。
J Med Toxicol. 2011 Jun;7(2):125-32. doi: 10.1007/s13181-011-0134-x.
5
Chronic cough due to occupational factors.职业因素所致的慢性咳嗽。
J Occup Med Toxicol. 2006 Feb 2;1:3. doi: 10.1186/1745-6673-1-3.
6
In vivo cytogenetic studies of the genotoxic effects of polymethyl methacrylate employed in orthopaedics.
J Mater Sci Mater Med. 1998 Apr;9(4):239-42. doi: 10.1023/a:1008844409003.
7
Complications of percutaneous vertebroplasty and their prevention.经皮椎体成形术的并发症及其预防
Skeletal Radiol. 2004 Sep;33(9):493-505. doi: 10.1007/s00256-004-0776-8. Epub 2004 Jun 17.
8
Exposure of medical personnel to methylmethacrylate vapor during percutaneous vertebroplasty.经皮椎体成形术中医务人员接触甲基丙烯酸甲酯蒸汽的情况。
AJNR Am J Neuroradiol. 1999 Feb;20(2):352-3.
本文引用的文献
1
[Methylmetacrylate, considerations with special reference to industrial hygiene].[甲基丙烯酸甲酯，特别涉及工业卫生的考量]
Gig Sanit. 1954 Oct;10:25-8.
2
Styrene and methyl methacrylate in the industrial environment as a risk factor of chronic obstructive lung disease.
Int Arch Occup Environ Health. 1982;51(2):151-7. doi: 10.1007/BF00378159.
3
Effects of methyl methacrylate monomer vapors on respiration and circulation in unanesthetized rats.甲基丙烯酸甲酯单体蒸汽对未麻醉大鼠呼吸和循环的影响。
J Prosthet Dent. 1982 Sep;48(3):344-8. doi: 10.1016/0022-3913(82)90026-9.
4
Changes in the normal maximal expiratory flow-volume curve with growth and aging.正常最大呼气流量-容积曲线随生长和衰老的变化。
Am Rev Respir Dis. 1983 Jun;127(6):725-34. doi: 10.1164/arrd.1983.127.6.725.
5
Circadian variation of F.E.V. in shift workers.轮班工人第一秒用力呼气量的昼夜变化。
Br J Ind Med. 1969 Apr;26(2):121-5. doi: 10.1136/oem.26.2.121.
6
A histologic and hemodynamic study of the toxic effects of monomeric methyl methacrylate.甲基丙烯酸甲酯单体毒性作用的组织学和血液动力学研究
Clin Orthop Relat Res. 1973 Jan-Feb(90):262-70.
7
Methylmethacrylate: tissue distribution and pulmonary damage in rats following acute inhalation.甲基丙烯酸甲酯：大鼠急性吸入后的组织分布及肺部损伤
Res Commun Chem Pathol Pharmacol. 1985 Oct;50(1):151-4.
8
Lung function measurements over 21 days shiftwork in steelworkers from a strandcasting department.连铸车间炼钢工人21天轮班工作期间的肺功能测量。
Br J Ind Med. 1985 Sep;42(9):601-11. doi: 10.1136/oem.42.9.601.
9
The shape of the maximum expiratory flow volume curve.最大呼气流量容积曲线的形状。
Chest. 1988 Oct;94(4):799-806. doi: 10.1378/chest.94.4.799.
10
[Respiratory function disorders caused by agrochemical exposure].[农药接触引起的呼吸功能障碍]
Z Erkr Atmungsorgane. 1985;164(3):267-9.
Zotero 插件