Orellana J, Lieberman R M
Department of Ophthalmology, Mount Sinai School of Medicine, New York.
Br J Ophthalmol. 1993 Sep;77(9):555-8. doi: 10.1136/bjo.77.9.555.
Twelve macular holes in 12 patients underwent a pars plana vitrectomy and epiretinal membrane resection with intravitreal gas tamponade for repair of their macular holes. The patients had stage III macular holes and had previously undergone a normal funduscopic examination within 2 years. The patients have been followed for a mean of 14 months (range 12-18 months) postoperatively. The results show that visual acuity improvements were not seen until at least 6 months after surgery if the hole was closed successfully. Seven holes were closed (58.3%) and all improved their best corrected visual acuity by more than two Snellen lines. In the five eyes that did not demonstrate hole closure (41.6%), one eye improved by two lines as well. The other four eyes remained at their preoperative acuity. One eye developed a dialysis which responded to a fluid air exchange and cryopexy (8.3%). Three eyes developed minimal lenticular opacities during the follow up period (25%). One eye demonstrated an altered perifoveal pigment epithelium perhaps related to intraoperative light toxicity. Macular hole surgery can restore some central acuity even in patients with longstanding holes.
12例患者的12个黄斑裂孔接受了玻璃体切除术、视网膜前膜切除术及玻璃体腔内气体填充术以修复黄斑裂孔。这些患者均为Ⅲ期黄斑裂孔,且在2年内曾接受过正常的眼底检查。术后对患者进行了平均14个月(范围12 - 18个月)的随访。结果显示,如果裂孔成功闭合,视力改善至少要在术后6个月才会出现。7个裂孔闭合(58.3%),所有这些患者的最佳矫正视力均提高了超过两行Snellen视力表视标。在未显示裂孔闭合的5只眼中(41.6%),有1只眼视力也提高了两行。另外4只眼的视力维持在术前水平。1只眼发生了视网膜脱离,经液体空气交换及冷冻治疗后好转(8.3%)。3只眼在随访期间出现了轻度晶状体混浊(25%)。1只眼显示黄斑中心凹周围色素上皮改变,可能与术中光毒性有关。即使是长期存在黄斑裂孔的患者,黄斑裂孔手术也能恢复一定的中心视力。