Steigerwalt R D, Belcaro G, Cesarone M R, Laurora G, De Sanctis M T, Milazzo M
Angiology and Vascular Surgery Centre, Pierangeli Clinic, Pescara, Italy.
Eye (Lond). 1993;7 ( Pt 3):403-6. doi: 10.1038/eye.1993.79.
Using high-resolution Duplex scanning it is possible to evaluate the blood flow velocity in the central retinal artery of eyes of normal individuals. The flow velocity can be divided into its systolic and diastolic phases. Topical timolol maleate 0.5%, a non-selective beta-adrenergic receptor blocking agent, was then administered to one eye in each of the normals and the flow velocity was again recorded. The flow velocity improvement was significant, with a 43.58% increase in the systolic phase and a 61.53% increase in the diastolic phase. The diastolic component increased from 49.29% to 55.56%. The increased flow velocity may be due to a vasodilatory effect of timolol. The technique is briefly described and the significance of the results discussed.
使用高分辨率双功扫描可以评估正常个体眼睛视网膜中央动脉的血流速度。血流速度可分为收缩期和舒张期。然后，在每个正常个体的一只眼睛中局部应用0.5%的马来酸噻吗洛尔，这是一种非选择性β-肾上腺素能受体阻滞剂，之后再次记录血流速度。血流速度有显著改善，收缩期增加了43.58%，舒张期增加了61.53%。舒张成分从49.29%增加到55.56%。血流速度增加可能是由于噻吗洛尔的血管舒张作用。本文简要描述了该技术并讨论了结果的意义。
