Sled V D, Friedrich T, Leif H, Weiss H, Meinhardt S W, Fukumori Y, Calhoun M W, Gennis R B, Ohnishi T
Department of Biochemistry and Biophysics, University of Pennsylvania, Philadelphia 19104.
J Bioenerg Biomembr. 1993 Aug;25(4):347-56. doi: 10.1007/BF00762460.
Many bacteria contain proton-translocating membrane-bound NADH-quinone oxidoreductases (NDH-1), which demonstrate significant genetic, spectral, and kinetic similarity with their mitochondrial counterparts. This review is devoted to the comparative aspects of the iron-sulfur cluster composition of NDH-1 from the most well-studied bacterial systems to date.: Paracoccus denitrificans, Rhodobacter sphaeroides, Escherichia coli, and Thermus thermophilus. These bacterial systems provide useful models for the study of coupling Site I and contain all the essential parts of the electron-transfer and proton-translocating machinery of their eukaryotic counterparts.
许多细菌含有质子转运膜结合NADH-醌氧化还原酶（NDH-1），它们与其线粒体对应物在遗传、光谱和动力学方面表现出显著的相似性。本综述致力于比较迄今为止研究最深入的细菌系统中NDH-1的铁硫簇组成：反硝化副球菌、球形红杆菌、大肠杆菌和嗜热栖热菌。这些细菌系统为研究偶联位点I提供了有用的模型，并且包含了其真核对应物电子传递和质子转运机制的所有基本部分。
