Cheung A N, Khoo U S, Kwong K Y, Srivastava G, Collins R J
Department of Pathology, University of Hong Kong.
J Clin Pathol. 1993 Sep;46(9):849-51. doi: 10.1136/jcp.46.9.849.
To detect the presence of Epstein-Barr virus (EBV) in cases of vulval carcinoma in Chinese patients living in Hong Kong.
Formalin fixed, paraffin wax embedded blocks from eight cases of vulval carcinoma and six age matched controls of non-neoplastic vulval tissue were analysed for the presence of EBV DNA using the polymerase chain reaction (PCR).
EBV DNA was detected in only one of the eight cases of vulval carcinoma cases while it was detected in four out of the six control cases.
There is no demonstrable association between EBV and vulval carcinoma. Detection of EBV in non-neoplastic vulval epithelium highlights its ubiquitous presence in the lower female genital tract.
检测居住在香港的中国患者外阴癌病例中是否存在爱泼斯坦-巴尔病毒（EBV）。
采用聚合酶链反应（PCR）分析8例外阴癌福尔马林固定、石蜡包埋组织块及6例年龄匹配的非肿瘤性外阴组织对照中EBV DNA的存在情况。
8例外阴癌病例中仅1例检测到EBV DNA，而6例对照病例中有4例检测到。
EBV与外阴癌之间无明显关联。在非肿瘤性外阴上皮中检测到EBV凸显了其在下女性生殖道中的普遍存在。
