Delaney J C
Clin Allergy. 1976 Jul;6(4):365-8. doi: 10.1111/j.1365-2222.1976.tb01917.x.
The onset of increased airways obstruction after analgesic ingestion by asthmatics with analgesic idiosyncrasy suggests an immediate type 1 allergic response. The effect of sodium cromoglycate (DSCG) on this response was assessed in nineteen patients with this syndrome. DSCG prevented asthmatic attacks in only three patients, all non-atopic, suggesting that analgesic idiosyncrasy is not an allergic disorder, The effectiveness of DSCG in preventing asthmatic attacks in some patients with analgesic idiosyncrasy would suggest that a trial of this preparation should be undertaken before commencing continuous corticosteroid therapy.
患有镇痛药特异反应的哮喘患者在摄入镇痛药后气道阻塞加剧，这表明是即刻的1型过敏反应。在19名患有该综合征的患者中评估了色甘酸钠（DSCG）对这种反应的影响。DSCG仅在3名患者（均为非特应性患者）中预防了哮喘发作，这表明镇痛药特异反应不是一种过敏性疾病。DSCG对一些患有镇痛药特异反应的患者预防哮喘发作有效，这表明在开始持续皮质类固醇治疗之前应试用这种制剂。
