慢性支气管炎和肺气肿合并肺心病的长期家庭氧疗。
Long-term domiciliary oxygen therapy in cor pulmonale complicating chronic bronchitis and emphysema.
作者信息
Leggett R J, Cooke N J, Clancy L, Leitch A G, Kirby B J, Flenley D C
出版信息
Thorax. 1976 Aug;31(4):414-8. doi: 10.1136/thx.31.4.414.
Abstract
Ten patients with cor pulmonale complicating severe chronic bronchitis and emphysema have been treated with 2 litres/min of oxygen for prolonged periods in the day, at home, over 12 to 62 months. Two patients died after 12 and 36 months of treatment. Pulmonary arterial pressure was reduced in seven patients, and red cell mass in eight, when the oxygen was given for over 15 hours in the day. Hospital inpatient treatment was greatly reduced following the start of long-term oxygen treatment in all patients. This treatment is expensive, and a controlled trial is necessary to establish its definitive place and cost-effectiveness, but the results of such a current Medical Research Council trial will not be available for a further two years.
摘要
10例合并严重慢性支气管炎和肺气肿的肺心病患者在家中每天长时间（12至62个月）接受2升/分钟的氧气治疗。两名患者在治疗12个月和36个月后死亡。当每天吸氧超过15小时时，7例患者的肺动脉压降低，8例患者的红细胞量减少。所有患者开始长期氧疗后，住院治疗次数大幅减少。这种治疗费用昂贵，需要进行对照试验以确定其确切地位和成本效益，但医学研究委员会目前的此类试验结果在未来两年内无法获得。
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