Leggett R J, Flenley D C
Br Med J. 1977 Jul 9;2(6079):84-6. doi: 10.1136/bmj.2.6079.84.
Breathing 30% oxygen during exercise alleviated arterial hypoxaemia and reduced minute ventilation in patients with severe chronic bronchitis. A similar level of oxygen (2 or 4 litres of oxygen/minute) from nasal prongs also increased their exercise tolerance, as assessed by the distance that they could walk on the level in 12 minutes. Nevertheless, a single-blind controlled study showed that the effort of carrying their portable supply of liquid oxygen, in the Union Carbide Oxygen Walker, abolished this gain in exercise tolerance. The improvement in walking distance was restored when oxygen on exercise was provided by wheeling the oxygen walker on a light-weight shopping trolley.
运动期间呼吸30%的氧气可缓解重度慢性支气管炎患者的动脉低氧血症并降低分钟通气量。通过鼻导管提供类似水平的氧气(2或4升/分钟)也可提高他们的运动耐力,这通过他们在平地上12分钟内能够行走的距离来评估。然而,一项单盲对照研究表明,使用联合碳化物氧气步行器携带便携式液态氧的行为抵消了运动耐力的这种提高。当用轻便购物车推着氧气步行器在运动时提供氧气时,行走距离的改善得以恢复。