Wechsung E, Houvenaghel A
Laboratory of Veterinary Physiology, University Centre of Antwerp, Belgium.
Zentralbl Veterinarmed A. 1993 Sep;40(7):533-8. doi: 10.1111/j.1439-0442.1993.tb00662.x.
In conscious piglets with electrodes implanted in the wall of the antrum pylori, duodenum, jejunum and ileum, the influence of intravenous infusion of serotonin (5-HT), 4 micrograms/kg/min for 2 hours, on gastrointestinal electrical activity and arterial pressure was examined. 5-HT was without significant influence on antral electrical activity and arterial pressure. In the small intestinal parts 5-HT provoked a shortening of the interval of the migrating myoelectrical complex (MMC) by reducing the duration of phase I and phase II activities, and an increase in propagation velocity. 5-HT also induced an increase in phase III activity. A possible involvement of 5-HT in the initiation and propagation of the MMC is suggested.
在已将电极植入幽门窦、十二指肠、空肠和回肠壁的清醒仔猪中，研究了以4微克/千克/分钟的速度静脉输注血清素（5-羟色胺，5-HT）2小时对胃肠电活动和动脉血压的影响。5-HT对胃窦电活动和动脉血压无显著影响。在小肠部分，5-HT通过缩短I期和II期活动的持续时间，使移行性肌电复合波（MMC）的间隔缩短，并使传播速度增加。5-HT还诱导III期活动增加。提示5-HT可能参与了MMC的起始和传播。
