[绞股蓝化学成分的研究]

[Studies on chemical constituents of Gynostemma compressum].

作者信息

Ding S L, Zhu Z Y

机构信息

Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Beijing.

出版信息

Yao Xue Xue Bao. 1993;28(5):364-9.

PMID:8237382

Abstract

Four new saponins, gycomoside I-IV, were isolated from the aerial part of Gynostemma compressum X.X. Chen et D.R. Liang. The structures were elucidated on the basis of spectral and chemical evidences as 1 beta,3 beta,12 beta,20(S),26-pentahydroxy-dammar- 24(25)-en-20(S)-O-beta-D-glucopyranosyl1-6--beta-D-glucopyranoside (gycomoside I); 1 beta,3 beta,12 beta,20(S)-tetrahydroxy-dammar-24(25)-en-3-O- beta-D-glucopyranosyl-20(S)-O-beta-D-glucopyranosyl1-6--beta-D-glu copyranoside (gycomoside II); 1 beta,3 beta,12 beta,20(S), 26-pentahydroxy-dammar-24(25)-en-20(S)-O- beta-D-glucopyranoside (gycomoside III) and 1 beta,3 beta,12 beta,20(S),26-pentahydroxy-dammar-24(25)- en-3-O-beta-D-glucopyranosyl-20(S)-O-beta-D-glucopyranosyl1-6--bet a-D-glucopyranoside (gycomoside IV).

摘要

从绞股蓝X.X. Chen和D.R. Liang的地上部分分离出四种新皂苷，即绞股蓝皂苷I-IV。基于光谱和化学证据阐明其结构分别为1β，3β，12β，20(S)，26-五羟基-达玛-24(25)-烯-20(S)-O-β-D-吡喃葡萄糖基-1-6--β-D-吡喃葡萄糖苷（绞股蓝皂苷I）；1β，3β，12β，20(S)-四羟基-达玛-24(25)-烯-3-O-β-D-吡喃葡萄糖基-20(S)-O-β-D-吡喃葡萄糖基-1-6--β-D-吡喃葡萄糖苷（绞股蓝皂苷II）；1β，3β，12β，20(S)，26-五羟基-达玛-24(25)-烯-20(S)-O-β-D-吡喃葡萄糖苷（绞股蓝皂苷III）和1β，3β，12β，20(S)，26-五羟基-达玛-24(25)-烯-3-O-β-D-吡喃葡萄糖基-20(S)-O-β-D-吡喃葡萄糖基-1-6--β-D-吡喃葡萄糖苷（绞股蓝皂苷IV）。