Jousset F X
Ann Microbiol (Paris). 1976 May-Jun;127(4):529-44.
The host range of the C picornavirus of Drosophila melanogaster was studied, using numerous strains of Drosophila together with four other genera of diptera and two species of lepidoptera. C virus was injected into the different hosts and serially passaged in them. The extracts from each passage were biologically assayed on virus free D. melanogaster. Four different situations were found. 1) A high level of multiplication leading, in 45 strains of Drosophilidae, to the early death of the hosts. This phenomenon was particularly related to the subgroup melanogaster and in the dipteron Ceratitis capitata. The titre of the virus in this latter insect was high as in D. melanogaster, but its cellular tropism was wider. 2) An active viral multiplication but without symptoms, in two strains of D. immigrans and in the lepidopteron Galleria mellonella. In these two insects, the viral titre was clearly inferior to that observed in D. melanogaster. 3) Maintenance of the virus, without multiplication in the dipteron Calliphora erythrocephala and the lepidopteron Arctia caja. In these insects, the decrease in virus titre was directly related to the dilution factor at each passage. 4) Rapid disappearance of the virus, in the mosquitoes Culex pipiens and Aedes aegypti. The host range of C virus is compared to that of Sigma virus of Drosophila and of two other picornaviruses of insects.
利用黑腹果蝇的众多品系以及双翅目的其他四个属和鳞翅目的两个物种，对黑腹果蝇的C微小核糖核酸病毒的宿主范围进行了研究。将C病毒注入不同宿主并在其中连续传代。每次传代的提取物在无病毒的黑腹果蝇上进行生物学检测。发现了四种不同情况。1）高水平增殖，导致45个果蝇科品系的宿主早期死亡。这种现象与黑腹果蝇亚组以及双翅目昆虫地中海实蝇特别相关。后一种昆虫体内的病毒滴度与黑腹果蝇中的一样高，但其细胞嗜性更广。2）在两种移民果蝇品系和鳞翅目昆虫大蜡螟中病毒活跃增殖但无症状。在这两种昆虫中，病毒滴度明显低于在黑腹果蝇中观察到的滴度。3）病毒在双翅目昆虫红头丽蝇和鳞翅目昆虫红带鬼脸天蛾中得以维持，但不增殖。在这些昆虫中，病毒滴度的下降与每次传代时的稀释因子直接相关。4）病毒在蚊子库蚊和埃及伊蚊中迅速消失。将C病毒的宿主范围与果蝇的西格玛病毒以及昆虫的另外两种微小核糖核酸病毒的宿主范围进行了比较。
