紧密连接的结构与调控
The structure and regulation of tight junctions.
作者信息
Anderson J M, Balda M S, Fanning A S
机构信息
Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut 06510.
出版信息
Curr Opin Cell Biol. 1993 Oct;5(5):772-8. doi: 10.1016/0955-0674(93)90024-k.
PMID:8240820
Abstract
Tight junctions create a paracellular barrier between both epithelial and endothelial cells. Recent advances have helped define their molecular composition and regulation. Studies in cultured cell lines provide new insights into how assembly and barrier properties may be controlled by signal transduction cascades.
摘要
紧密连接在上皮细胞和内皮细胞之间形成细胞旁屏障。最近的进展有助于明确其分子组成和调控机制。对培养细胞系的研究为信号转导级联如何控制紧密连接的组装和屏障特性提供了新的见解。
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