• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

A conserved signal transduction pathway regulating the activity of the rel-like proteins dorsal and NF-kappa B.

作者信息

Wasserman S A

机构信息

Department of Biochemistry, UT Southwestern Medical Center, Dallas 75235-9038.

出版信息

Mol Biol Cell. 1993 Aug;4(8):767-71. doi: 10.1091/mbc.4.8.767.

DOI:10.1091/mbc.4.8.767
PMID:8241564
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC300990/
Abstract
摘要

相似文献

1
A conserved signal transduction pathway regulating the activity of the rel-like proteins dorsal and NF-kappa B.一条保守的信号转导途径，调节类rel蛋白背侧蛋白和核因子κB的活性。
Mol Biol Cell. 1993 Aug;4(8):767-71. doi: 10.1091/mbc.4.8.767.
2
The Dorsal-related immunity factor (Dif) can define the dorsal-ventral axis of polarity in the Drosophila embryo.背侧相关免疫因子（Dif）可确定果蝇胚胎中背腹极性轴。
Development. 1998 Jun;125(11):2159-69. doi: 10.1242/dev.125.11.2159.
3
Direct association of pp40/I kappa B beta with rel/NF-kappa B transcription factors: role of ankyrin repeats in the inhibition of DNA binding activity.pp40/IκBβ与rel/NF-κB转录因子的直接关联：锚蛋白重复序列在抑制DNA结合活性中的作用。
Proc Natl Acad Sci U S A. 1992 May 15;89(10):4333-7. doi: 10.1073/pnas.89.10.4333.
4
Vertebrate Rel proteins exhibit Dorsal-like activities in early Drosophila embryogenesis.脊椎动物的Rel蛋白在果蝇胚胎发育早期表现出类似背侧的活性。
Dev Dyn. 2006 Apr;235(4):949-57. doi: 10.1002/dvdy.20713.
5
Rel signalling pathway and the melanotic tumour phenotype of Drosophila.
Biochem Soc Trans. 1996 Feb;24(1):39-44. doi: 10.1042/bst0240039.
6
The predominantly HEAT-like motif structure of huntingtin and its association and coincident nuclear entry with dorsal, an NF-kB/Rel/dorsal family transcription factor.亨廷顿蛋白主要的类HEAT基序结构及其与NF-kB/Rel/背侧家族转录因子背侧的关联以及同时进入细胞核的情况。
BMC Neurosci. 2002 Oct 14;3:15. doi: 10.1186/1471-2202-3-15.
7
The rel-associated pp40 protein prevents DNA binding of Rel and NF-kappa B: relationship with I kappa B beta and regulation by phosphorylation.与rel相关的pp40蛋白可阻止Rel和NF-κB与DNA结合：与IκBβ的关系及磷酸化调控
Genes Dev. 1991 Aug;5(8):1464-76. doi: 10.1101/gad.5.8.1464.
8
p105 and p98 precursor proteins play an active role in NF-kappa B-mediated signal transduction.p105和p98前体蛋白在核因子κB介导的信号转导中发挥积极作用。
Genes Dev. 1993 Apr;7(4):705-18. doi: 10.1101/gad.7.4.705.
9
Signal transduction. Dorsal developments.
Nature. 1994 Dec 8;372(6506):500-1. doi: 10.1038/372500a0.
10
Mechanisms of enhanced nuclear translocation of the transcription factors c-Rel and NF-kappa B by CD28 costimulation in human T lymphocytes.
Ann N Y Acad Sci. 1995 Sep 7;766:220-3. doi: 10.1111/j.1749-6632.1995.tb26669.x.

引用本文的文献

1
Study of Drug Targets Associated With Oncogenesis and Cancer Cell Survival and the Therapeutic Activity of Engineered Ashwagandha Extract Having Differential Withanolide Constitutions.与肿瘤发生和癌细胞存活相关的药物靶点研究以及具有不同醉茄内酯成分的工程化印度人参提取物的治疗活性
Integr Cancer Ther. 2024 Jan-Dec;23:15347354231223499. doi: 10.1177/15347354231223499.
2
PPARγ ameliorated LPS induced inflammation of HEK cell line expressing both human Toll-like receptor 4 (TLR4) and MD2.过氧化物酶体增殖物激活受体γ（PPARγ）改善了脂多糖诱导的同时表达人Toll样受体4（TLR4）和髓样分化蛋白2（MD2）的人胚肾细胞系（HEK）的炎症反应。
Cytotechnology. 2016 Aug;68(4):1337-48. doi: 10.1007/s10616-015-9893-6. Epub 2015 Jul 30.
3
An effector Peptide family required for Drosophila toll-mediated immunity.果蝇Toll介导的免疫所需的效应肽家族。
PLoS Pathog. 2015 Apr 27;11(4):e1004876. doi: 10.1371/journal.ppat.1004876. eCollection 2015 Apr.
4
Porphyromonas gingivalis promotes invasion of oral squamous cell carcinoma through induction of proMMP9 and its activation.牙龈卟啉单胞菌通过诱导前基质金属蛋白酶9及其激活来促进口腔鳞状细胞癌的侵袭。
Cell Microbiol. 2014 Jan;16(1):131-45. doi: 10.1111/cmi.12211. Epub 2013 Sep 19.
5
Expression of Toll-like receptor 4 in neonatal cord blood mononuclear cells in patients with preeclampsia.子痫前期患者新生儿脐血单个核细胞中Toll样受体4的表达
J Huazhong Univ Sci Technolog Med Sci. 2010 Oct;30(5):615-9. doi: 10.1007/s11596-010-0552-z. Epub 2010 Nov 10.
6
Toll-like receptors: molecular mechanisms of the mammalian immune response.Toll样受体：哺乳动物免疫反应的分子机制
Immunology. 2000 Sep;101(1):1-10. doi: 10.1046/j.1365-2567.2000.00093.x.
7
TAFII mutations disrupt Dorsal activation in the Drosophila embryo.TAFII 突变会破坏果蝇胚胎中的 Dorsal 激活。
Proc Natl Acad Sci U S A. 1998 Nov 10;95(23):13483-8. doi: 10.1073/pnas.95.23.13483.
8
A family of human receptors structurally related to Drosophila Toll.一类在结构上与果蝇Toll受体相关的人类受体。
Proc Natl Acad Sci U S A. 1998 Jan 20;95(2):588-93. doi: 10.1073/pnas.95.2.588.
9
Self-defense: the fruit fly style.自卫：果蝇式的。
Proc Natl Acad Sci U S A. 1998 Jan 20;95(2):429-30. doi: 10.1073/pnas.95.2.429.
10
A role for CKII phosphorylation of the cactus PEST domain in dorsoventral patterning of the Drosophila embryo.CKII磷酸化仙人掌PEST结构域在果蝇胚胎背腹模式形成中的作用。
Genes Dev. 1997 Dec 15;11(24):3413-22. doi: 10.1101/gad.11.24.3413.

本文引用的文献

1
Binding affinities and cooperative interactions with bHLH activators delimit threshold responses to the dorsal gradient morphogen.与bHLH激活剂的结合亲和力和协同相互作用界定了对背侧梯度形态发生素的阈值反应。
Cell. 1993 Mar 12;72(5):741-52. doi: 10.1016/0092-8674(93)90402-c.
2
pelle encodes a protein kinase required to establish dorsoventral polarity in the Drosophila embryo.佩勒基因编码一种在果蝇胚胎中建立背腹极性所需的蛋白激酶。
Cell. 1993 Feb 26;72(4):515-25. doi: 10.1016/0092-8674(93)90071-w.
3
Activation of the sphingomyelin signaling pathway in intact EL4 cells and in a cell-free system by IL-1 beta.白细胞介素-1β在完整的EL4细胞和无细胞体系中激活鞘磷脂信号通路。
Science. 1993 Jan 22;259(5094):519-22. doi: 10.1126/science.8424175.
4
Information for the dorsal--ventral pattern of the Drosophila embryo is stored as maternal mRNA.果蝇胚胎背腹模式的信息以母体mRNA的形式储存。
Nature. 1984;311(5983):223-7. doi: 10.1038/311223a0.
5
Establishment of dorsal-ventral polarity in the Drosophila embryo: the induction of polarity by the Toll gene product.果蝇胚胎背腹极性的建立：Toll基因产物对极性的诱导
Cell. 1985 Oct;42(3):791-8. doi: 10.1016/0092-8674(85)90275-2.
6
Establishment of dorsal-ventral polarity in the Drosophila embryo: genetic studies on the role of the Toll gene product.果蝇胚胎背腹极性的建立：Toll基因产物作用的遗传学研究
Cell. 1985 Oct;42(3):779-89. doi: 10.1016/0092-8674(85)90274-0.
7
I kappa B: a specific inhibitor of the NF-kappa B transcription factor.IκB：NF-κB转录因子的特异性抑制剂。
Science. 1988 Oct 28;242(4878):540-6. doi: 10.1126/science.3140380.
8
Activation of DNA-binding activity in an apparently cytoplasmic precursor of the NF-kappa B transcription factor.NF-κB转录因子一个明显位于细胞质的前体中DNA结合活性的激活。
Cell. 1988 Apr 22;53(2):211-7. doi: 10.1016/0092-8674(88)90382-0.
9
Dorsal, an embryonic polarity gene in Drosophila, is homologous to the vertebrate proto-oncogene, c-rel.背侧蛋白是果蝇中的一种胚胎极性基因，与脊椎动物原癌基因c-rel同源。
Science. 1987 Oct 30;238(4827):692-4. doi: 10.1126/science.3118464.
10
cDNA expression cloning of the IL-1 receptor, a member of the immunoglobulin superfamily.白细胞介素-1受体的cDNA表达克隆，免疫球蛋白超家族成员之一。
Science. 1988 Jul 29;241(4865):585-9. doi: 10.1126/science.2969618.